Results 41 to 50 of about 314,589 (303)
, 2013 Translation is an important step in gene expression. The initiation of translation is phylogenetically diverse, since currently five different initiation mechanisms are known.
Jörg Soppa +14 more
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Comparison of computational methods for identifying translation initiation sites in EST data
BMC Bioinformatics, 2004 Background Expressed Sequence Tag (EST) sequences are generally single-strand, single-pass sequences, only 200–600 nucleotides long, contain errors resulting in frame shifts, and represent different parts of their parent cDNA.
Ellis Lynda BM +2 more
doaj +1 more source
Mechanisms of microRNA mediated gene silencing in C. elegans [PDF]
, 2009 Mechanisms of microRNA mediated gene silencing in C. elegans Xavier Ding Dissertation abstract microRNAs (miRNAs) are a large family of small non-coding RNAs, which post-transcriptionally repress numerous genes; a type of regulation which is ...
Ding, Xavier
core +1 more source
Noncanonical Translation Initiation in Eukaryotes [PDF]
Cold Spring Harbor Perspectives in Biology, 2018 The vast majority of eukaryotic messenger RNAs (mRNAs) initiate translation through a canonical, cap-dependent mechanism requiring a free 5' end and 5' cap and several initiation factors to form a translationally active ribosome. Stresses such as hypoxia, apoptosis, starvation, and viral infection down-regulate cap-dependent translation during which ...
Thaddaeus, Kwan, Sunnie R, Thompson
openaire +2 more sources
Cell Reports, 2018 Summary: Protein translation in eukaryotes is cell-cycle dependent, with translation rates more robust in G1 phase of the cell cycle than in mitosis. However, whether the fundamental cell-cycle control machinery directly activates protein translation ...
Tai An +4 more
doaj +1 more source
Self-Initiation of Translation of mRNAs Devoid of Translational Initiators in Escherichia coli
Folia Biologica, 2001 Recent studies have shown that the canonical SD-anti-SD interaction is dispensable for the initiation of translation of certain mRNAs in Escherichia coli . In this study the cat and tetR genes were modified to ...
V, Kolev, A, Berzal-Herranz, I, Ivanov
openaire +2 more sources
Profiling of Small Ribosomal Subunits Reveals Modes and Regulation of Translation Initiation
Cell Reports, 2020 Summary: Translation initiation is often attributed as the rate-determining step of eukaryotic protein synthesis and key to gene expression control. Despite this centrality, the series of steps involved in this process is poorly understood.
Adam Giess +8 more
doaj +1 more source
RNA-Binding Proteins as Regulators of Internal Initiation of Viral mRNA Translation
Viruses, 2022 Viruses are obligate intracellular parasites that depend on the host’s protein synthesis machinery for translating their mRNAs. The viral mRNA (vRNA) competes with the host mRNA to recruit the translational machinery, including ribosomes, tRNAs, and the ...
Brenda López-Ulloa +3 more
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, 2012 ATP binding cassette proteins are a large and diverse family of molecular machines and include transmembrane transporter, chromosome maintenance and DNA repair proteins, and translation factors.
Hopfner, Karl-Peter
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A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho +7 more
wiley +1 more source