Results 161 to 170 of about 75,107 (299)

Elder Clowning Interventions for Persons With Dementia in Long-Term Care: A Systematic Review and Metasynthesis of Qualitative Research. [PDF]

Dementia (London)
Roberts SJ, Luckett T, Ivynian S, DiGiacomo M.   +3 more
europepmc   +1 more source

The Role of Microbiota Metabolites Propionic Acid, p‐Cresol, and 4‐Ethylphenyl Sulfate in Autism Susceptibility: A Systematic Review

Autism Research, EarlyView.
ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis.
Laura Sandoni, Lisa Asta, Nicole Giompaolo, Rinvil Renaldi, Alberto Amaretti, Maddalena Rossi, Antonio M. Persico   +6 more
wiley   +1 more source

'Our role is to listen more than entertain': A qualitative study of techniques used by Laughter Care Specialists with people who have dementia in long-term care. [PDF]

Australas J Ageing
DiGiacomo M, Roberts SJ, Luckett T, Symons D, Ellis G, Kochovska S, Warner T, Currow DC, Parker D, Payne K, Agar MR.   +10 more
europepmc   +1 more source

Occurrence and Correlates of Suicidal Thoughts Among Young Autistic Users of a Mental Health App

Autism Research, EarlyView.
ABSTRACT Young autistic people experience disproportionately high rates of mental health challenges, yet little is known about factors associated with suicidality in this group. This study leveraged anonymous self‐report data to identify correlates of suicidal thoughts among 365 young users (aged approximately 11–25 years) of a mental health app in the
T. L. Procyshyn, E. M. Weir, M. Pelton, T. Chikaura, H. Hodges, K. Comley, S. Godson, C. Allison, S. Baron‐Cohen   +8 more
wiley   +1 more source

"It changed the atmosphere, but how long will it last?": healthcare professionals' experiences of an intervention to improve positive communication in intensive care. [PDF]

Ann Intensive Care
Barth A, Cecconi M, Boulanger C, Azoulay E, Barnes NK.   +4 more
europepmc   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

Visual content and thematic analyses of images shared on social media before and after episodes of self-harm in a UK clinical youth sample. [PDF]

BMJ Open
Bye A, Trevillion K, Wilson-Lemoine E, Leightley D, Carter B, Liakata M, Hopper J, Dutta R.   +7 more
europepmc   +1 more source

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko, Titiaan E. Post, Pamela K. Strugala, Erica S. Klaassen, Linda E. Klumpers, Saco J. de Visser, Cristina Sempio, Jost Klawitter, Jules A. A. C. Heuberger, Geert J. Groeneveld   +9 more
wiley   +1 more source

The aqueous humour dynamics in primary angle closure disease: a computational study. [PDF]

Br J Ophthalmol
Fu L, Liu X, Zhang L, Lou J, Zheng X, Wang X, Lin H, Guo L, Wang K, Wang Y, Kan M, Liang Y.   +11 more
europepmc   +1 more source

Pharmacokinetics and pharmacodynamics of intravenous and oral (S)‐ketamine: Investigating metabolite contribution to subjective effects

British Journal of Clinical Pharmacology, EarlyView.
Aims Oral administration of (S)‐ketamine for treatment‐resistant depression (TRD), as alternative to the registered intranasal or off‐label intravenous administrations, has high potential. However, it is characterized by an extensive first‐pass metabolism, resulting in low (S)‐ketamine exposure and high levels of active metabolites, including (S ...
Marije E. Otto, Gabriël E. Jacobs, Joost C. van Mechelen, Laura G. J. M. Borghans, Johan G. C. van Hasselt, Linda B. S. Aulin   +5 more
wiley   +1 more source