Results 111 to 120 of about 6,898,913 (302)

Les expressions locatives dans le texte descriptif et leur traduction en français : l'exemple de Solaris de Stanisław Lem

Études romanes de Brno, 2013
Locative expression seems to be one of essential elements of space description. Basing on examples drawn from Solaris by Stanisław Lem and its translation into French, the purpose of this article is to examine the impact of locative expressions ...
Katarzyna Piwnik
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

MATEO : MAchine Translation Evaluation Online

, 2023
We present MAchine Translation Evaluation Online (MATEO), a project that aims to facilitate machine translation (MT) evaluation by means of an easy-to-use web interface that can evaluate given machine translations with a battery of automatic metrics.
Vanroy, BramUGent0001615296528020026585439747705382060000-0002-4622-8364C50B0474-7EE0-11E7-B38D-2BA4AD28A064, Popovic, Majaeditor, Brenner, Juditheditor, Nurminen, Maryeditor, Mikhailov, Mikhaileditor, Forcada, Mikeleditor, Alvarez Vidal, Sergieditor, Scarton, Carolinaeditor, Ranasinghe, Tharindueditor, Koponen, Maariteditor, Aranberri, Noraeditor, Parra Escartín, Carlaeditor, Latomaa, Sirkkueditor, Nunziatini, Maraeditor, Tezcan, ArdaLW220020058519838020017673550000-0002-8707-6176E4E9C51C-9502-11E3-A4F6-4F4B11BDE39D, Macken, LieveLW228020002457680000-0001-7516-7487F93DB0F6-F0ED-11E1-A9DE-61C894A0A6B4, Vanmassenhove, Evaeditor, Schierl, Frederikeeditor, Moniz, Helenaeditor   +18 more
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Students’ Perception of Using the Literal Translation Method to Translate Descriptive Text

ELT Forum: Journal of English Language Teaching
Literal translation is commonly used by student translators because it helps them retain the words and sentence structures of the source text. However, its use in translating descriptive texts can become problematic when closely following the original ...
Farid Akhbar Fardillah, Ummi Nur Laila Sulistyani   +1 more
doaj   +1 more source

Audiovisual Translation in the Age of Netflix [PDF]

peer reviewedThis paper examines Netflix’s most prominent transnational strategies and their impact on the AVT sector in general, and the work of subtitlers in particular.
MOREAU, Eponine
core   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source