Results 131 to 140 of about 6,898,913 (302)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
English-Arabic Cultural Effect in Translation: A Relevance Theory Perspective
, 2016 This article is co-authored with Prof. Alaa Eddin Hussain. Monograph. Original workThis study is framed within a competence-oriented model which provides the target text (TT) receiver with communicative clues.
Khuddro, Ahmad
core
What Could the Translation of a ‘Retelling’ Imply for Translation Studies?
, 2019 The purpose of this study is to scrutinize the implications that The Canterbury Tales: A Retelling (2009) by Peter Ackroyd and its Turkish translation hold for Translation Studies.
Hilal Öztürk Baydere +1 more
core +2 more sources
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Specification-Aware Machine Translation and Evaluation for Purpose Alignment
Proceedings of the Tenth Conference on Machine TranslationIn professional settings, translation is guided by communicative goals and client needs, often formalized as specifications. While existing evaluation frameworks acknowledge the importance of such specifications, these specifications are often treated only implicitly in machine translation (MT) research.
Yoko Kayano, Saku Sugawara
openaire +3 more sources
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Legal discourse on the translation of ‘The Runway Jury’, by Grisham: a network of differences
Gragoatá, 2016 In discussing the translation options for the best-seller 'The Runway Jury' by John Grisham, the purpose of this paper is to contemplate translation practices whose purpose would be to produce a fluent translated discourse concealing the translator's ...
Érika Nogueira de Andrade Stupiello
doaj
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source