Results 41 to 50 of about 423,019 (240)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Feminist Translation: Translator's Subjectivity, Strategies and Influences

Journal of Higher Education Research, 2021
Feminist translation theory is the academic fruit of the further development of feminist movement and also the portrayal of women's reflection fueled by feminism. Based on Skopos theory, the paper explores how translator's subjectivity acts in translation activities from the feminist perspective, aiming to reveal the relationship between feminist ...
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Translation Model, Translation Analysis, Translation Strategy: An Integrated Methodology

Procedia - Social and Behavioral Sciences, 2014
AbstractThe paper revisits the concepts of translation model, translation analysis, and translation strategy from an integrated perspective. Translation modeling is reconsidered in terms of a paradigm shift and a distinction between a process-oriented (descriptive) model and an action-oriented (prescriptive) model.
openaire   +2 more sources

Translation Strategies in Translating Toer’s Bumi Manusia

International Journal of Linguistics, Literature and Translation, 2020
Translating Toer’s Bumi Manusia means translating Indonesian culture. As its translator, Lane has to provide English translation which is enjoyable, readable, and acceptable both culturally and linguistically. He solves the problem of non-equivalence by applying translation strategies.
Wedhowerti, Wedhowerti, Oentari, Brigitta Sita, Setiajid, Harris Hermansyah, Adji, Susilawati Endah Peni   +3 more
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Untangling and Re-spinning the Web: Translations of Metaphor in Tanizaki’s “Shisei”

Translation and Interpreting : the International Journal of Translation and Interpreting Research, 2009
This article evaluates strategies for translating metaphor from Japanese to English adopted by five translators of Japanese author Tanizaki Jun’ichiro’s short story “Shisei”.
Shani Tobias
doaj  

DEFINITION OF TRANSLATION, TRANSLATION STRATEGY, TRANSLATION PROCEDURE, TRANSLATION METHOD, TRANSLATION TECHNIQUE, TRANSLATION TRANSFORMATION

InterConf, 2021
In modern linguistics, one of the current topics is the study of the relationships between languages, as one of the main means of transmission of meanings and the socio-cultural reality. Among the many challenges studied by the modern linguistics, an important place is the study of the linguistic aspects of cross-language speech activity, which is ...
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source