An exploratory case study investigating the implementation of a novel knowledge translation strategy in a pandemic: the Pandemic Practice Champion. [PDF]
Stevens B +7 more
europepmc +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Exploring conceptualizations of knowledge translation, transfer and exchange across public health in one UK region: a qualitative mapping study [PDF]
Objectives - Knowledge translation (KT) is becoming common vocabulary, but as a concept it is not clearly defined. Many related terms exist; these are often used interchangeably and given multiple interpretations.
Steven, Alison +5 more
core +1 more source
Lattice score based data cleaning for phrase-based statistical machine translation [PDF]
Statistical machine translation relies heavily on parallel corpora to train its models for translation tasks. While more and more bilingual corpora are readily available, the quality of the sentence pairs should be taken into consideration.
Way, Andy +2 more
core +2 more sources
Die vertaling en lokalisering van Terminologie van het tolken vir ’n Suid-Afrikaanse teikengehoor
Although much research is currently undertaken on interpreting in South Africa, the profession and academic discourse lack standardised interpreting terminology, especially in the indigenous languages.
Cornelius, Eleanor , Pienaar, Marné
doaj +1 more source
Diffusion of Innovations-Informed Knowledge Translation Strategy to Implement Optimal Safe Nursing Workforce Policy in Practice. [PDF]
Park CS, Lee S, Kim H, Kabak M.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Operetta in Turkey: A case study of Gün’s translation of Strauss’s Die Fledermaus
The genre operetta has long found itself a place in the musical polysystem of Turkey and become one of the borrowed forms of art symbolizing modernity through Turkey’s Westernization process.
Soy, Özlem Şahin +2 more
core +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source

