Results 141 to 150 of about 4,480,419 (303)
Translation of Sounds for Children: an Example of a Multimodal Work
, 2023 Translation of poetry, particularly intended for children, has always been considered as one of the most problematic and challenging sub-fields of literary translation.
Hastürkoğlu, Gökçen +1 more
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ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Strategies of Literary Translation
Journal of Siberian Federal University. Humanities & Social Sciences, 2015 Литературный перевод представляет собой широкий круг деятельности, охватывая не только перевод художественной литературы (поэзии и прозы), но и научно-популярной литературы, очерков, газетных материалов, дневников, мемуаров и т.п. Различные виды текстов, требующих литературной обработки, вызывают необходимость различных переводческих стратегий и ...
openaire +3 more sources
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Interpretation and translation in Guy Delisle’s Shenzhen [PDF]
, 2012 As a piece of travel writing describing Guy Delisle’s trip to China as an animator, Shenzhen: A Travelogue from China (2006) is readable in relation to translation as a practice and as a metaphor.
Evans, Jonathan
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Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Problem solving strategies in translation Problem solving strategies in translation
Ilha do Desterro, 2008 Space does not permit us to describe in detail the state of the art in the greatly neglected field of problem solving strategies in translation. This can be treated in a separate paper as very little has been published on the subject in English; scholars who read German may consult Henschelmann’s survey article “Zur Beschreibung und Klassifizierung von
openaire +1 more source