Results 141 to 150 of about 1,343,152 (300)

Interprofessional Resource Centre: a knowledge translation strategy

open access: yesAdvances in Medical Education and Practice, 2011
Christine Patterson1,2, Julie Vohra1, David Price3, Gladys Peachey1, Heather Arthur1,4, Patricia Ellis1, Rob Mariani5, Paul Dymel5, Ellen Spencer5, Kevin Timms5, Ellis Westwood51School of Nursing, Faculty of Health Sciences, McMaster University, Hamilton,
Christine Patterson   +3 more
doaj  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

PHILOSOPHICAL TEXT AS A TRANSLATION OBJECT (BASED ON THE WORK OF S. A. KRIPKE “WITTGENSTEIN ON RULES AND PRIVATE LANGUAGE”)

open access: yesМногоязычие в образовательном пространстве
The article examines the problems of informative translation, in particular, translating philosophical texts. The relevance of this research lies in the fact that philosophical texts are used not only by philosophers, but also by scientists of various ...
Yu.A. Borisenko, D.S. Vladimirov
doaj  

Die interkulturelle Übersetzungsstrategie von „Dao“ im deutschen Übersetzungswerk Laotse. Tao Te King. Das Buch des Alten vom SINN und LEBEN von Richard Wilhelm – Eine kontrastive Forschung im Hinblick auf Übersetzungsdialog der Intertextualität und Interkulturalität.

open access: yesInterkulturelles Forum der deutsch-chinesischen Kommunikation
Die Bedeutungen des Schriftzeichens „Dao“ in Tao Te King von Laotse, einem der chinesischen klassischen philosophischen Werke, sind hochkomplex. Aufgrund dessen gestaltet sich eine treffende Übersetzung des Wortes „Dao“ ins Deutsche als komplex.
Wang Jingyi
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Entre rivalité et accomplissement : Un cœur simple de Gustave Flaubert retraduit en polonais

open access: yesAcademic Journal of Modern Philology
The paper aims to explore the translation project of two polish versions of Gustave Flaubert’s short story Un cœur simple. The translators’ decisions at the level of proper names, syntax, lexis and discursive forms demonstrate the choice of domesticating
Magdalena Mitura
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

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