Results 151 to 160 of about 4,480,419 (303)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Lost in Knowledge Translation: Moving Towards a Clearer Picture? Mapping the conceptualisation of knowledge translation, transfer and exchange across public health in the North East [PDF]

open access: yes, 2012
Over recent decades the concept of evidence-based practice in health care has become part of the language of practitioners, policymakers and researchers.
Steven, Alison   +2 more
core  

Interprofessional Resource Centre: a knowledge translation strategy

open access: yesAdvances in Medical Education and Practice, 2011
Christine Patterson1,2, Julie Vohra1, David Price3, Gladys Peachey1, Heather Arthur1,4, Patricia Ellis1, Rob Mariani5, Paul Dymel5, Ellen Spencer5, Kevin Timms5, Ellis Westwood51School of Nursing, Faculty of Health Sciences, McMaster University, Hamilton,
Christine Patterson   +3 more
doaj  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

An Investigation into Automatic Translation of Prepositions in IT Technical Documentation from English to Chinese [PDF]

open access: yes, 2010
Machine Translation (MT) technology has been widely used in the localisation industry to boost the productivity of professional translators. However, due to the high quality of translation expected, the translation performance of an MT system in ...
Sun, Yanli
core   +1 more source

Die interkulturelle Übersetzungsstrategie von „Dao“ im deutschen Übersetzungswerk Laotse. Tao Te King. Das Buch des Alten vom SINN und LEBEN von Richard Wilhelm – Eine kontrastive Forschung im Hinblick auf Übersetzungsdialog der Intertextualität und Interkulturalität.

open access: yesInterkulturelles Forum der deutsch-chinesischen Kommunikation
Die Bedeutungen des Schriftzeichens „Dao“ in Tao Te King von Laotse, einem der chinesischen klassischen philosophischen Werke, sind hochkomplex. Aufgrund dessen gestaltet sich eine treffende Übersetzung des Wortes „Dao“ ins Deutsche als komplex.
Wang Jingyi
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Entre rivalité et accomplissement : Un cœur simple de Gustave Flaubert retraduit en polonais

open access: yesAcademic Journal of Modern Philology
The paper aims to explore the translation project of two polish versions of Gustave Flaubert’s short story Un cœur simple. The translators’ decisions at the level of proper names, syntax, lexis and discursive forms demonstrate the choice of domesticating
Magdalena Mitura
doaj   +1 more source

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