Results 131 to 140 of about 419,375 (265)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Impact of an organization-wide knowledge translation strategy to support evidence-informed public health decision making. [PDF]

BMC Public Health, 2018
Dobbins M, Traynor RL, Workentine S, Yousefi-Nooraie R, Yost J.   +4 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Putting family into family-based obesity prevention: enhancing participant engagement through a novel integrated knowledge translation strategy. [PDF]

BMC Med Res Methodol, 2018
Walton K, Ambrose T, Annis A, Ma DW, Haines J, Guelph Family Health Study Family Advisory Council; on behalf of the Guelph Family Health Study.   +5 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Implementation of a knowledge translation strategy to promote early evidence-based rehabilitation for children with cerebral palsy. [PDF]

Dev Med Child Neurol
Hanson J, Majnemer A, Shikako K, Dahan-Oliel N, Pietrangelo F, Dickson L, Steven E, Iliopoulos G, Ogourtsova T.   +8 more
europepmc   +1 more source

Scoping review of toolkits as a knowledge translation strategy in health. [PDF]

BMC Med Inform Decis Mak, 2014
Barac R, Stein S, Bruce B, Barwick M.
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Our Voices, Our Stories-A Multi-Method Knowledge Translation Strategy for Advancing Inclusivity and Creating Trauma-Informed Wound Care. [PDF]

Int Wound J
Costa IG, Strachan RK, Levine D, Kuper I, Santorelli S, Plazas PC, Botros M, Bajnok I, Philips C.   +8 more
europepmc   +1 more source

Osteoporosis prescribing in long-term care: impact of a provincial knowledge translation strategy. [PDF]

Can J Aging, 2015
Kennedy CC, Ioannidis G, Thabane L, Adachi JD, O'Donnell D, Giangregorio LM, Pickard LE, Papaioannou A.   +7 more
europepmc   +1 more source