Results 61 to 70 of about 2,149,735 (308)

Can a stationary Bianchi black brane have momentum along the direction with no translational symmetry? [PDF]

, 2014
Bianchi black branes (black brane solutions with homogeneous but anisotropic horizons classified by the Bianchi type) provide a simple holographic setting with lattice structures taken into account.
Iizuka, Norihiro, Ishibashi, Akihiro, Maeda, Kengo   +2 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Genome-wide analysis of growth phase-dependent translational and transcriptional regulation in halophilic archaea : research article [PDF]

, 2007
Background Differential expression of genes can be regulated on many different levels. Most global studies of gene regulation concentrate on transcript level regulation, and very few global analyses of differential translational efficiencies exist.
Hammelmann, Mathias, Lange, Christian, Oesterhelt, Dieter, Raddatz, Günter, Schuster, Stephan C., Soppa, Jörg (Prof. Dr.), Twellmeyer, Jens, Zaigler, Alexander   +7 more
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Blackfeet innovation pathways to food sovereignty: sustainability through indigenous-led research partnerships

Frontiers in Sustainable Food Systems
The Blackfeet Nation in northwestern Montana, United States, is implementing its Agriculture Resource Management Plan (ARMP), an Indigenous-led, sustainable agriculture plan prioritizing economic development for Indigenous producers, intergenerational ...
Kimberly L. Paul, Kristin T. Ruppel, Kristin T. Ruppel, Micaela M. Young, Laura Caplins, Jill Falcon Ramaker, Christopher J. Carter, William B. Seeley, Christen Falcon, Andrew Berger   +9 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

No-horizon theorem for vacuum gravity with spacelike G1 isometry groups

, 2003
We show that (3+1) vacuum spacetimes admitting a global, spacelike, one-parameter Lie group of isometries of translational type cannot contain apparent horizons. The only assumption made is that of the existence of a global spacelike Killing vector field
B.K. Berger, C.W. Misner, D. Ida, E.T. Newman, E.T. Newman, F.B. Fuller, J. Eels, M.A. Pelath, R. Geroch, R. Geroch, S.L. Shapiro, S.M.C.V. Gonçalves, S.W. Hawking, Sérgio M. C. V. Gonçalves, T.A. Apostolatos, V. Moncrief, Y. Nutku   +16 more
core   +1 more source

Limitless translation limits translation [PDF]

Nature, 2017
Evidence has now been found that ribosomes — the cell’s translational apparatus — can pass beyond the main protein-coding region of messenger RNAs to form ‘traffic jams’ that inhibit protein expression. Evidence has now been found that ribosomes — the cell’s translational apparatus — can pass beyond the main protein-coding region of messenger RNAs to ...
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Evaluation of Andrographis paniculata in a mouse model of influenza A viral infection using oral administration and a translationally relevant dose

Frontiers in Pharmacology
IntroductionEthnobotanically, Andrographis paniculata aerial parts have been used to alleviate the symptoms of viral infections, colds, and sore throats.
Kashif Shamim, Grace C. Burnett, Jin Zhang, Nessma H. Ahmed, Shabana I. Khan, Shabana I. Khan, Amar G. Chittiboyina, Amar G. Chittiboyina, Amar G. Chittiboyina, Ikhlas A. Khan, Ikhlas A. Khan, Gailen D. Marshall, Gailen D. Marshall, John T. Bates, John T. Bates, John T. Bates, Nirmal D. Pugh   +16 more
doaj   +1 more source