Results 81 to 90 of about 2,149,735 (308)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Frontiers in Neuroscience, 2020 The understanding of human and non-human microstructural brain alterations in the course of neurodegenerative diseases has substantially improved by the non-invasive magnetic resonance imaging (MRI) technique of diffusion tensor imaging (DTI).
Hans-Peter Müller +4 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Open-Label Phase 1/2 Study of Daratumumab-Based Desensitization Before Kidney Transplantation
Kidney International ReportsIntroduction: The safety and benefit of the anti-CD38 monoclonal antibody daratumumab, which induces lysis of antibody-producing plasma cells in sensitized patients prior to kidney transplantation, remain to be determined.
Caroline Pilon +12 more
doaj +1 more source
Relative and center-of-mass motion in the attractive Bose-Hubbard model
, 2012 We present first-principle numerical calculations for few particle solutions of the attractive Bose-Hubbard model with periodic boundary conditions.
A. Bohr +6 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Rotational intermittency and turbulence induced lift experienced by large particles in a turbulent flow [PDF]
, 2010 The motion of a large, neutrally buoyant, particle, freely advected by a turbulent flow is determined experimentally. We demonstrate that both the translational and angular accelerations exhibit very wide probability distributions, a manifestation of ...
Alain Pumir +6 more
core +3 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
On the new translational shape invariant potentials
, 2011 Recently, several authors have found new translational shape invariant potentials not present in classic classifications like that of Infeld and Hull.
Arturo Ramos +11 more
core +1 more source