Results 71 to 80 of about 2,149,735 (308)

Black hole elasticity and gapped transverse phonons in holography

open access: yes, 2018
We study the elastic response of planar black hole (BH) solutions in a simple class of holographic models with broken translational invariance. We compute the transverse quasi-normal mode spectrum and the propagation speed of the lowest energy mode.
Alberte, Lasma   +4 more
core   +1 more source

Translational Invariance and the Anisotropy of the Cosmic Microwave Background [PDF]

open access: yes, 2010
Primordial quantum fluctuations produced by inflation are conventionally assumed to be statistically homogeneous, a consequence of translational invariance.
C. M. Will   +6 more
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Innovative micro physiological systems for vaccine development

open access: yesHuman Vaccines & Immunotherapeutics
Micro Physiological systems (MPS) are biomimetic platforms that reconstitute the complex architecture of human organs and tissues in vitro. MPSs have the capacity to improve clinical development pipelines as they address certain translational limitations
Kendra Reynaud   +4 more
doaj   +1 more source

Dual-topology insertion of a dual-topology membrane protein. [PDF]

open access: yes, 2015
Some membrane transporters are dual-topology dimers in which the subunits have inverted transmembrane topology. How a cell manages to generate equal populations of two opposite topologies from the same polypeptide chain remains unclear.
Bowie, James U   +2 more
core  

From Ejtm (European Journal of Translational Myology) to Ejt3M (European Journal of Translational Myology, Mobility, Medicine) [PDF]

open access: yes, 2018
This first 2018 issue of the European Journal of Translational Myology presents many novelties, that demonstrate that the journal is vital and expanding its authorship, readership and relevance from focused fields of biology, physiology, diagnostic ...
Adamo, Sergio
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Multimodal AI-based systems in major depressive disorder: a review of clinical and translational applications

open access: yesFrontiers in Digital Health
Major Depressive Disorder (MDD) is one of the most prevalent and disabling psychiatric conditions worldwide, involving alterations in mood regulation, cognitive function, sleep, and physiological systems.
Claudio Crema   +7 more
doaj   +1 more source

Kinetic Model of Translational Autoregulation

open access: yes, 2018
We investigate dynamics of a kinetic model of inhibitory autoregulation as exemplified when a protein inhibits its own production by interfering with its messenger RNA, known in molecular biology as translational autoregulation.
Kellman, Michael E., Tyng, Vivian
core   +2 more sources

Translation, Translation, Translation. [PDF]

open access: yesCirculation research, 2018
Heusch, Gerd   +2 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy