Results 71 to 80 of about 933,800 (312)
Regulation of mRNA translation during mitosis
eLife, 2015 Passage through mitosis is driven by precisely-timed changes in transcriptional regulation and protein degradation. However, the importance of translational regulation during mitosis remains poorly understood. Here, using ribosome profiling, we find both
Marvin E Tanenbaum +3 more
doaj +1 more source
Thinking Outside the Frame: Impacting Genomes Capacity by Programmed Ribosomal Frameshifting
Frontiers in Molecular Biosciences, 2022 Translation facilitates the transfer of the genetic information stored in the genome via messenger RNAs to a functional protein and is therefore one of the most fundamental cellular processes.
Ricarda J. Riegger +3 more
doaj +1 more source
Citrullination – small change with a great consequence [PDF]
, 2013 Citrullination is one of the possible post-translational modifications of proteins. It is based on a conversion of L-arginine residue (L-Arg) to L-citrulline residue (L-Cit). The reaction is catalyzed by peptidylarginine deiminases (PAD). The change of L-
Gogól Mariusz
core +2 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Crocodilepox Virus Protein 157 Is an Independently Evolved Inhibitor of Protein Kinase R
Viruses, 2022 Crocodilepox virus (CRV) belongs to the Poxviridae family and mainly infects hatchling and juvenile Nile crocodiles. Most poxviruses encode inhibitors of the host antiviral protein kinase R (PKR), which is activated by viral double-stranded (ds) RNA ...
M. Julhasur Rahman +3 more
doaj +1 more source
Translational regulation in spermatogenesis [PDF]
, 2009 Thesis (Ph. D. in Agricultural Science)--University of Tsukuba, (A), no.
木村 正紀
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Post-translational regulation of FOXO [PDF]
Acta Biochimica et Biophysica Sinica, 2012 The Forkhead box O (FOXO) family transcription factors play critical roles in a series of cellular processes, including the cell cycle, cell death, metabolism, and oxidative stress resistance. FOXO proteins are subject to several post-translational modifications, which are closely related to their activity.
Qi, Xie, Jing, Chen, Zengqiang, Yuan
openaire +2 more sources
Kinetic Model of Translational Autoregulation
, 2018 We investigate dynamics of a kinetic model of inhibitory autoregulation as exemplified when a protein inhibits its own production by interfering with its messenger RNA, known in molecular biology as translational autoregulation.
Kellman, Michael E., Tyng, Vivian
core +2 more sources
Ribosome traffic on mRNAs maps to gene ontology : genome-wide quantification of translation initiation rates and polysome size regulation [PDF]
, 2013 Peer reviewedPublisher ...
Ciandrini, Luca +2 more
core +3 more sources