Results 51 to 60 of about 617,976 (302)

Translational Regulation in the Chloroplast [PDF]

open access: yesPlant Physiology, 1997
TRANSLATIONAL REGULATION IN THE CHLOROPLAST Gene expression is potentially amenable to regulation at different points along the linear path from a gene to a functional protein. To control gene expression the regulatory event has to occur at a limiting rate.
openaire   +2 more sources

Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan [PDF]

open access: yes, 2015
Several pathways modulating longevity and stress resistance converge on translation by targeting ribosomal proteins or initiation factors, but whether this involves modifications of ribosomal RNA is unclear.
Wilson, Iain B H   +31 more
core   +1 more source

Combined Analysis of the Time-Resolved Transcriptome and Proteome of Plant Pathogen Xanthomonas oryzae pv. oryzae

open access: yesFrontiers in Microbiology, 2021
Xanthomonas oryzae pv. oryzae (Xoo) is a plant pathogen responsible for causing bacterial blight in rice. The immediate alterations in Xoo upon initial contact with rice are essential for pathogenesis. We studied time-resolved genome-wide gene expression
Seunghwan Kim   +6 more
doaj   +1 more source

Post-translational regulation of PTEN [PDF]

open access: yesOncogene, 2008
PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor regulates a variety of cellular processes including cell proliferation, growth, migration and death. This master regulator itself is also under deliberative regulation.
X, Wang, X, Jiang
openaire   +2 more sources

Metazoan tsRNAs: Biogenesis, Evolution and Regulatory Functions

open access: yesNon-Coding RNA, 2019
Transfer RNA-derived small RNAs (tsRNAs) are an emerging class of regulatory non-coding RNAs that play important roles in post-transcriptional regulation across a variety of biological processes.
Shengqian Dou, Yirong Wang, Jian Lu
doaj   +1 more source

Decoupling the impact of microRNAs on translational repression versus RNA degradation in embryonic stem cells

open access: yeseLife, 2018
Translation and mRNA degradation are intimately connected, yet the mechanisms that link them are not fully understood. Here, we studied these mechanisms in embryonic stem cells (ESCs). Transcripts showed a wide range of stabilities, which correlated with
Jacob W Freimer, TJ Hu, Robert Blelloch
doaj   +1 more source

Loss of m6A Methyltransferase METTL5 Promotes Cardiac Hypertrophy Through Epitranscriptomic Control of SUZ12 Expression

open access: yesFrontiers in Cardiovascular Medicine, 2022
Enhancement of protein synthesis from mRNA translation is one of the key steps supporting cardiomyocyte hypertrophy during cardiac remodeling. The methyltransferase-like5 (METTL5), which catalyzes m6A modification of 18S rRNA at position A1832, has been ...
Yanchuang Han   +28 more
doaj   +1 more source

Codon usage suggests that translational selection has a major impact on protein expression in trypanosomatids. [PDF]

open access: yes, 2008
BACKGROUND: Different proteins are required in widely different quantities to build a living cell. In most organisms, transcription control makes a major contribution to differential expression.
Horn, David   +2 more
core   +1 more source

The global downregulation of protein synthesis observed during hepatogenic maturation is associated with a decrease in TOP mRNA translation

open access: yesStem Cell Reports, 2023
Summary: Translational regulation is of paramount importance for proteome remodeling during stem cell differentiation at both the global and the transcript-specific levels.
Marino Caruso   +13 more
doaj   +1 more source

Extensive translational regulation during seed germination revealed by polysomal profiling [PDF]

open access: yes, 2017
This work investigates the extent of translational regulation during seed germination. The polysome occupancy of each gene is determined by genome-wide profiling of total mRNA and polysome-associated mRNA.
Bing Bai   +16 more
core   +2 more sources

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