Results 31 to 40 of about 933,800 (312)

Using the Knowledge of Post-transcriptional Regulations to Guide Gene Selections for Molecular Breeding in Soybean

open access: yesFrontiers in Plant Science, 2022
The omics approaches allow the scientific community to successfully identify genomic regions associated with traits of interest for marker-assisted breeding.
Yee-Shan Ku   +5 more
doaj   +1 more source

Metazoan tsRNAs: Biogenesis, Evolution and Regulatory Functions

open access: yesNon-Coding RNA, 2019
Transfer RNA-derived small RNAs (tsRNAs) are an emerging class of regulatory non-coding RNAs that play important roles in post-transcriptional regulation across a variety of biological processes.
Shengqian Dou, Yirong Wang, Jian Lu
doaj   +1 more source

Roles of transcriptional and translational control mechanisms in regulation of ribosomal protein synthesis in Escherichia coli [PDF]

open access: yes, 2017
Bacterial ribosome biogenesis is tightly regulated to match nutritional conditions and to prevent formation of defective ribosomal particles. InEscherichia coli, most ribosomal protein (r-protein) synthesis is coordinated with rRNA synthesis by a ...
Burgos, Hector L   +3 more
core   +3 more sources

Combined Analysis of the Time-Resolved Transcriptome and Proteome of Plant Pathogen Xanthomonas oryzae pv. oryzae

open access: yesFrontiers in Microbiology, 2021
Xanthomonas oryzae pv. oryzae (Xoo) is a plant pathogen responsible for causing bacterial blight in rice. The immediate alterations in Xoo upon initial contact with rice are essential for pathogenesis. We studied time-resolved genome-wide gene expression
Seunghwan Kim   +6 more
doaj   +1 more source

The multifaceted roles of PI3Kγ in hypertension, vascular biology, and inflammation [PDF]

open access: yes, 2016
PI3Kγ is a multifaceted protein, crucially involved in cardiovascular and immune systems. Several studies described the biological and physiological functions of this enzyme in the regulation of cardiovascular system, while others stressed its role in ...
Carnevale, Daniela   +2 more
core   +2 more sources

Decoupling the impact of microRNAs on translational repression versus RNA degradation in embryonic stem cells

open access: yeseLife, 2018
Translation and mRNA degradation are intimately connected, yet the mechanisms that link them are not fully understood. Here, we studied these mechanisms in embryonic stem cells (ESCs). Transcripts showed a wide range of stabilities, which correlated with
Jacob W Freimer, TJ Hu, Robert Blelloch
doaj   +1 more source

Genome-wide analysis of growth phase-dependent translational and transcriptional regulation in halophilic archaea [PDF]

open access: yes, 2007
Background Differential expression of genes can be regulated on many different levels. Most global studies of gene regulation concentrate on transcript level regulation, and very few global analyses of differential translational efficiencies exist.
Christian Lange   +7 more
core   +1 more source

Human eRF1 Translation Regulation

open access: yesMolecular Biology
Abstract Eukaryotic translation release factor eRF1 is an important cellular protein that plays a key role in translation termination, nonsense-mediated mRNA decay (NMD), and readthrough of stop codons. The amount of eRF1 in the cell influences all these processes. The mechanism of regulation of eRF1 translation through
A V, Shuvalov   +4 more
openaire   +2 more sources

Post-translational regulation of PTEN [PDF]

open access: yesOncogene, 2008
PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor regulates a variety of cellular processes including cell proliferation, growth, migration and death. This master regulator itself is also under deliberative regulation.
X, Wang, X, Jiang
openaire   +2 more sources

Loss of m6A Methyltransferase METTL5 Promotes Cardiac Hypertrophy Through Epitranscriptomic Control of SUZ12 Expression

open access: yesFrontiers in Cardiovascular Medicine, 2022
Enhancement of protein synthesis from mRNA translation is one of the key steps supporting cardiomyocyte hypertrophy during cardiac remodeling. The methyltransferase-like5 (METTL5), which catalyzes m6A modification of 18S rRNA at position A1832, has been ...
Yanchuang Han   +28 more
doaj   +1 more source

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