Results 11 to 20 of about 617,976 (302)
The Translational Regulation in mTOR Pathway
Biomolecules, 2022 The mechanistic/mammalian target of rapamycin (mTOR) plays a master role in cell proliferation and growth in response to insulin, amino acids, energy levels, and oxygen. mTOR can coordinate upstream signals with downstream effectors, including transcriptional and translational apparatuses to regulate fundamental cellular processes such as energy ...
Yanming Lu, Weilan Piao, Hua Jin
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Extensive allele‐specific translational regulation in hybrid mice [PDF]
Molecular Systems Biology, 2015 Translational regulation is mediated through the interaction between diffusible trans‐factors and cis‐elements residing within mRNA transcripts. In contrast to extensively studied transcriptional regulation, cis‐regulation on translation remains ...
Jingyi Hou +6 more
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PLoS ONE, 2009 Recently a first genome-wide analysis of translational regulation using prokaryotic species had been performed which revealed that regulation of translational efficiency plays an important role in haloarchaea.
Mariam Brenneis, Jörg Soppa
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A tail of translational regulation [PDF]
eLife, 2017 An RNA-binding protein called PABPC1 has an important role in determining protein synthesis rates and hypertrophy in the heart.
Gillian A Gray, Nicola K Gray
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Diverse roles of biomolecular condensation in eukaryotic translational regulation
RNA Biology, 2023 Biomolecular condensates, forming membrane-less organelles, orchestrate the sub-cellular compartment to execute designated biological processes.
Yuhan Zhang +3 more
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Molecular Systems Biology, 2016 Transcription initiated at alternative sites can produce mRNA isoforms with different 5ʹUTRs, which are potentially subjected to differential translational regulation.
Xi Wang +3 more
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Translational Regulation in Hepatocellular Carcinogenesis
Drug Design, Development and Therapy, 2021 Suzana Bracic Tomazic,1,2,* Christoph Schatz,3,* Johannes Haybaeck3,4 1Department of Pathology, Hospital Graz II, Graz, 8020, Austria; 2Faculty of Medicine, University of Maribor, Maribor, 2000, Slovenia; 3Institute of Pathology, Neuropathology ...
Bracic Tomazic S, Schatz C, Haybaeck J
doaj +4 more sources
Fine-Tuning the Expression of Duplicate Genes by Translational Regulation in Arabidopsis and Maize
Frontiers in Plant Science, 2019 Plant genomes are extensively shaped by various types of gene duplication. However, in this active area of investigation, the vast majority of studies focus on the sequence and transcription of duplicate genes, leaving open the question of how ...
Sishuo Wang +3 more
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Mechanisms of mitochondrial translational regulation [PDF]
IUBMB Life, 2013 AbstractThe mitochondrial oxidative phosphorylation system is formed by multimeric enzymes. In the yeast Saccharomyces cerevisiae, the bc1 complex, cytochrome c oxidase and the F1FO ATP synthase contain subunits of dual genetic origin. It has been recently established that key subunits of these enzymes, translated on mitochondrial ribosomes, are the ...
Fontanesi, Flavia
openaire +3 more sources
Yeast: Translation Regulation and Localized Translation
Microorganisms, 2023 Translation regulation and localized translation are essential for protein synthesis, controlling all aspects of cellular function in health and disease [...]
Ayala Shiber, Yoav S. Arava
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