Results 41 to 50 of about 617,976 (302)

Intercepting IRE1 kinase‐FMRP signaling prevents atherosclerosis progression

EMBO Molecular Medicine, 2022
Fragile X Mental Retardation protein (FMRP), widely known for its role in hereditary intellectual disability, is an RNA‐binding protein (RBP) that controls translation of select mRNAs.
Zehra Yildirim, Sabyasachi Baboo, Syed M Hamid, Asli E Dogan, Ozlem Tufanli, Sabrina Robichaud, Christina Emerton, Jolene K Diedrich, Hasan Vatandaslar, Fotis Nikolos, Yanghong Gu, Takao Iwawaki, Elizabeth Tarling, Mireille Ouimet, David L Nelson, John R Yates, Peter Walter, Ebru Erbay   +17 more
doaj   +1 more source

Overlapping signals for translational regulation and packaging of influenza A virus segment 2 [PDF]

, 2011
Influenza A virus segment 2 mRNA expresses three polypeptides: PB1, PB1-F2 and PB1-N40, from AUGs 1, 4 and 5 respectively. Two short open reading frames (sORFs) initiated by AUGs 2 and 3 are also present.
J. K. Taubenberger, Taubenberger, J.K., Digard, P., McCarthy, John E G, Edmund T. Rolls, J.R. Gog, Wise, Helen M., Amy J. Claydon, John E. G. Mccarthy, M. D. Curran, J.K. Taubenberger, H. M. Wise, Eyers, Claire, Eyers, Claire E., Claydon, AJ, P. Digard, Beynon, RJ, Deco Gustavo, McCarthy, JEG, Dalton, Rosa Maria, Kannambath, Shichina, E.C. Anderson, Rolls, Edmund T, Tristan J. Webb, Helen M. Wise, B. W. Jagger, Julia R. Gog, E. C. Anderson, Curran, M.D., Paul Digard, B.W. Jagger, Jagger, Brett W., H.M. Wise, R.M. Dalton, Claydon, Amy J., Anderson, E.C., Jeffery K. Taubenberger, Li, N, Tristan J Webb, Drummond, Sheona P., Deco, Gustavo, Hildyard, John, Webb, Tristan J., Edmund T Rolls, Gustavo Deco, Reamtong, O, Eyers, CE, Jagger, B.W., Helena Firczuk, C. Barbezange, Drummond, SP, Curran, Martin D., Jianfeng Feng, Robert J. Beynon, Webb Tristan J., John Hildyard, Taubenberger, Jeffery, Rolls, Edmund T., J. R. Gog, Feng Jianfeng, Firczuk, H, Sheona P. Drummond, Cyril Barbezange, Li, Ning, Onrapak Reamtong, Wise, H.M., Brett W. Jagger, Kannambath, S, Digard, Paul, Gog, Julia R., Gog, J.R., Anderson, Emma C., McCarthy, John E. G., Martin D. Curran, Shichina Kannambath, R. M. Dalton, Rosa M. Dalton, Barbezange, Cyril, Hildyard, J, Rolls Edmund T., Feng, Jianfeng, Barbezange, C., Dalton, R.M., Beynon, Robert J., M.D. Curran, Reamtong, Onrapak, Beynon, R. J. (Robert J.), Ning Li, Claire E. Eyers, Emma C. Anderson, Firczuk, Helena   +90 more
core   +1 more source

mRNA regulation in the "C. elegans" germ line [PDF]

, 2011
The C. elegans germ line relies heavily on post-transcriptional regulation of gene expression but the scale of mRNA regulation in the germ line is still unknown.
Scheckel, Claudia
core   +1 more source

Targeted insertion of regulatory elements enables translational enhancement in rice

Frontiers in Plant Science, 2023
In-locus editing of agronomically-important genes to optimize their spatiotemporal expression is becoming an important breeding approach. Compared to intensive studies on mRNA transcription, manipulating protein translation by genome editing has not been
Rundong Shen, Rundong Shen, Rundong Shen, Qi Yao, Qi Yao, Dating Zhong, Dating Zhong, Xuening Zhang, Xuening Zhang, Xinbo Li, Xinbo Li, Xinbo Li, Xuesong Cao, Chao Dong, Chao Dong, Yifu Tian, Yifu Tian, Yifu Tian, Jian-Kang Zhu, Jian-Kang Zhu, Yuming Lu, Yuming Lu   +21 more
doaj   +1 more source

Translational Regulation of Duplicated Gene Expression Evolution in Allopolyploid Cotton. [PDF]

Genes (Basel)
Polyploidy, a prevalent event in plant evolution, drives phenotypic diversification and speciation. While transcriptional changes and regulation in polyploids have been extensively studied, the translational level impact remains largely unexplored.
Fu G, Luo H, Jia J, Hou M, Hu G.
europepmc   +2 more sources

Regulation of neuronal excitability through pumilio-dependent control of a sodium channel gene [PDF]

, 2004
Dynamic changes in synaptic connectivity and strength, which occur during both embryonic development and learning, have the tendency to destabilize neural circuits.
Baines, Richard A.; id_orcid, Baines, Richard A., Mee, Christopher J., Moffat, Kevin G., Pym, Edward C G, Pym, Edward C. G.   +5 more
core   +1 more source

RNA modification-mediated translational control in immune cells

RNA Biology, 2023
RNA modifications play a vital role in multiple pathways of mRNA metabolism, and translational regulation is essential for immune cells to promptly respond to stimuli and adapt to the microenvironment.
Yujuan Zhang, Weiguo Hu, Hua-Bing Li
doaj   +1 more source

Using the Knowledge of Post-transcriptional Regulations to Guide Gene Selections for Molecular Breeding in Soybean

Frontiers in Plant Science, 2022
The omics approaches allow the scientific community to successfully identify genomic regions associated with traits of interest for marker-assisted breeding.
Yee-Shan Ku, Ming-Yan Cheung, Sau-Shan Cheng, Muhammad Azhar Nadeem, Gyuhwa Chung, Hon-Ming Lam   +5 more
doaj   +1 more source

Regulation of Transcription and Translation by Hypoxia [PDF]

Cancer Biology & Therapy, 2004
The maintenance of oxygen (O2) homeostasis is critical for embryonic development and postnatal life. In response to hypoxia, higher eukaryotes have developed coordinated mechanisms at both the transcriptional and translational levels to cope with this stress.
Liping, Liu, M Celeste, Simon
openaire   +2 more sources

Emerging roles of mitochondria in animal regeneration

Cell Regeneration, 2023
The regeneration capacity after an injury is critical to the survival of living organisms. In animals, regeneration ability can be classified into five primary types: cellular, tissue, organ, structure, and whole-body regeneration.
Yun Zhao, Chong Gao, Xue Pan, Kai Lei
doaj   +1 more source