Results 31 to 40 of about 412,188 (300)

‘Why would you promote something that is less percent safer than a condom?’: Perspectives on partially effective HIV prevention technologies among key populations in South Africa

SAHARA-J, 2018
New biomedical prevention technologies (NPTs) for HIV, including oral Pre-Exposure Prophylaxis, and vaginal and rectal microbicides and HIV vaccines in development, may contribute substantially to controlling the HIV epidemic.
Clara Rubincam, Peter A. Newman, Millicent Atujuna, Linda-Gail Bekker   +3 more
doaj   +1 more source

Collaborative software for traditional and translational research

Human Genomics, 2012
Biomedical research has entered a period of renewed vigor with the introduction and rapid development of genomic technologies and next-generation sequencing methods.
Berman Ari E, Barnett William K, Mooney Sean D   +2 more
doaj   +1 more source

Biomedical Informatics Applications for Precision Management of Neurodegenerative Diseases [PDF]

, 2018
Modern medicine is in the midst of a revolution driven by “big data,” rapidly advancing computing power, and broader integration of technology into healthcare. Highly detailed and individualized profiles of both health and disease states are now possible,
Jimenez-Maggoria, Gustavo, Lombardo, Joseph, Miller, Justin B., Shan, Guogen   +3 more
core   +2 more sources

Translational medicine and the NIHR Biomedical Research Centre concept [PDF]

QJM, 2008
The realization of scientific discovery being delivered to patients for their clinical benefit is termed Translational Medicine. This requires the bridging of excellence in both basic scientific endeavour and clinical care. Whilst there is consensus that it is important to drive translation for the benefit of patient care, the mechanism whereby this is
Snape, K., Trembath, R. C., Lord, G. M.
openaire   +3 more sources

Using bibliometrics to evaluate outcomes and influence of translational biomedical research centers

Journal of Clinical and Translational Science, 2022
Introduction: Federal grant funding to support infrastructure development of translational biomedical research centers is a form of public health intervention.
Kristine M. Bragg, Gwen C. Marchand, Jonathan C. Hilpert, Jeffrey L. Cummings   +3 more
doaj   +1 more source

Investigación traslacional en el currículo de medicina: una propuesta de reforma desde la práctica docente. Reflexiones sobre la reforma curricular

Educación Médica
Resumen: La medicina o investigación traslacional es una nueva rama de la medicina, que promueve el desarrollo científico a partir de la estrecha relación entre la investigación básica, preclínica y clínica, lo cual ha generado importantes avances en la ...
Manuel Latorre Quintana, Álvaro Andrés Rivera, Diego Alejandro Vivas   +2 more
doaj   +1 more source

Nanoinformatics: developing new computing applications for nanomedicine [PDF]

, 2012
Nanoinformatics has recently emerged to address the need of computing applications at the nano level. In this regard, the authors have participated in various initiatives to identify its concepts, foundations and challenges.
Alberto Anguita, Alejandro Pazos, Antoine Geissbuhler, B Smith, BY Kim, C Kulikowski, C Rosse, CA Kulikowski, Casimir Kulikowski, Cristian Munteanu, D Dela Iglesia, David Perez-Rey, DG Thomas, Diana De la Iglesia, ED Green, F Martin-Sanchez, Fernando Gonzalez-Nilo, Fernando Martin-Sanchez, Ferran Sanz, George Potamias, Guillermo De la Calle, Guillermo Lopez-Campos, H Berman, IS Kohane, Isabel Hermosilla, Jose Crespo, Jose Maria Barreiro, Josipa Kern, Joyce A. Mitchell, Julio C. Facelli, K Jain, Luciano Milanesi, M Gerstein, M Viceconti, Martin Fritts, Miguel Garcia-Remesal, N Gordon, NA Baker, Nathan Baker, Norbert Graf, P Kiberstis, Paula Otero, Peter Ghazal, Pierre Grangeat, Rada Hussein, Raul E. Cachau, RB Altman, S Bewick, Sabine Koch, SI O’Donoghue, Sonia E. Benitez, V Maojo, V Maojo, V Maojo, V Maojo, Vassilis Moustakis, Victor Maojo, Victoria Lopez-Alonso, Yannick Legre   +58 more
core   +7 more sources

Poor Translatability of Biomedical Research Using Animals — A Narrative Review

Alternatives to Laboratory Animals, 2023
The failure rate for the translation of drugs from animal testing to human treatments remains at over 92%, where it has been for the past few decades. The majority of these failures are due to unexpected toxicity — that is, safety issues revealed in human trials that were not apparent in animal tests — or lack of efficacy.
Lindsay J. Marshall, Jarrod Bailey, Manuela Cassotta, Kathrin Herrmann, Francesca Pistollato   +4 more
openaire   +2 more sources

MODERN APPROACHES TO THE ORGANIZATION OF TRANSLATIONAL RESEARCH

Педиатрическая фармакология, 2014
The growing distance between fundamental science and clinical medicine may bring risk of decreasing effectiveness of biomedical research. Translational research is a relatively new concept; it implies application of fundamental research results to ...
A. S. Kolbin, R. A. Gapeshin, S. M. Malyshev   +2 more
doaj   +1 more source

A novel closed-chest porcine model of chronic ischemic heart failure suitable for experimental research in cardiovascular disease [PDF]

, 2013
Cardiac pathologies are among the leading causes of mortality and morbidity in industrialized countries, with myocardial infarction (MI) representing one of the major conditions leading to heart failure (HF).
Antonio Amodeo, BIONDI ZOCCAI, GIUSEPPE, CALOGERO, ANTONELLA, CAVARRETTA, Elena, CHIMENTI, ISOTTA, DE FALCO, ELENA, Fabrizio D'Ascenzo, FRATI, GIACOMO, Luca Pacini, MANCONE, Massimo, Maria Emiliana Caristo, MARULLO, Antonino, Marzia Lotrionte, Omar Leoni, PERUZZI, MARIANGELA, PETROZZA, Vincenzo   +15 more
core   +3 more sources