Results 111 to 120 of about 56,482 (306)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Behaviors That Eliminate Health Disparities for Racial and Ethnic Minorities: A Narrative Systematic Review [PDF]

open access: yes, 2012
Within the health care provider-health care recipient relationship the communication must be culturally competent to eliminate barriers to equitable health care for all Americans.
Keys, Truman Ryan
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Certification and Job Task Analysis (JTA): Establishing Validity of Translator Certification Examinations

open access: yesTranslation and Interpreting : the International Journal of Translation and Interpreting Research, 2013
Translator certification examinations are offered by many entities worldwide. This article considers the question of how such examinations can be strengthened by applying certification theory and practice.
Geoffrey S. Koby, Alan K. Melby
doaj  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Second language learning: finding ways to successfully integrate ICT resources and right strategies for language learning, translation and interpreting [PDF]

open access: yes, 2019
Second language learning: finding ways to integrate ICT resources and right strategies for language learning, translation and interpreting Second language learning has gained importance as language accreditations have become imperative for any ...
Pérez Carrasco, Míriam
core  

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

A mixed-methods study of Arab translator trainees’ experiences in field training: Competence gains and challenges

open access: yesAmpersand
Despite integrating practical components, such as field training, into translator training programs to bridge the theory-practice gap, views of Arab trainees on their experience during the field training period are under-researched.
Dana K. Mahadin
doaj   +1 more source

Working with Bilingual Corpora to Enhance Legal Translation Competence

open access: yesRomanian Journal of English Studies, 2018
Although there has been harmonisation work on translator training, different programmes still show a different focus. The current paper frames a training project aiming at developing Master’s students specialised translation competence while working with
Oțăt Diana
doaj   +1 more source

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