Results 71 to 80 of about 131,152 (300)

TRANSLATOR TRAINING BY DISTANCE LEARNING — A DUAL APPROACH1

open access: yesIndonesian Journal of Applied Linguistics, 2015
A variety of approaches have been adopted by institutions of higher education offering programmes in translator training. Some of these approaches are centred on early training; while others on socio-constructivism.
Karnedi Karnedi
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Technology and translator training

open access: yes, 2019
There is broad consensus in the literature that anyone who wishes to become a professional translator of pragmatic and technical texts should acquire an understanding of, and an ability to use and critically appraise, contemporary translation technologies.
openaire   +1 more source

How Should Translation Competence Be Taught: a Quest for a Better Approach in Translation Class [PDF]

open access: yes, 2015
It is widely agreed that the main aim of translation education is to develop students' translation competence, therefore most researches in translation education contexts focus on identifying the components of transla-tion competence and appropriate ...
Alim, C. N. (Condro)
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

The ethics of machine translation [PDF]

open access: yes, 2011
In this paper I first describe the two main branches in machine translation research. I then go to discuss why the second of these, statistical machine translation, can cause some malaise among translation scholars.
Kenny, Dorothy
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

La inserció laboral dels llicenciats de traducció i interpretació en l'àmbit jurídic [PDF]

open access: yes, 2007
En aquest article presentem els perfils professionals i les sortides professionals que ofereix l'àmbit jurídic als llicenciats de traducció i d'interpretació. Per a cada perfil esmentarem les característiques bàsiques.
Torres Hostench, Olga
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

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