Results 121 to 130 of about 24,647 (268)

High-throughput isolation and characterization of untagged membrane protein complexes: outer membrane complexes of Desulfovibrio vulgaris. [PDF]

, 2012
Cell membranes represent the "front line" of cellular defense and the interface between a cell and its environment. To determine the range of proteins and protein complexes that are present in the cell membranes of a target organism, we have utilized a ...
Allen, Simon, Biggin, Mark D, Brenner, Steven E, Chandonia, John-Marc, Fisher, Susan J, Geller, Jil T, Hall, Steven C, Hazen, Terry C, Jap, Bing K, Lam, Bonita R, Liu, Haichuan, Shatsky, Maxim, Singer, Mary E, Szakal, Evelin D, Walian, Peter J, Witkowska, H Ewa, Zeng, Lucy   +16 more
core  

Effects of Cannabidiol on TAFAZZIN‐Deficient B‐Lymphoblastoid Cells

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Deficiency of the cardiolipin remodeling enzyme TAFAZZIN causes Barth syndrome (BTHS), resulting in cardiolipin loss, monolysocardiolipin (MLCL) accumulation, and electron transport chain (ETC) abnormalities in B‐lymphoblastoid cells. Effects of the non‐psychotropic phytocannabinoid cannabidiol (CBD) were examined on B‐lymphoblastoid cells from ...
John Z. Chan, Antonia N. Berdeklis, Ming Rong Liu, Fasih A. Rahman, Michelle V. Tomczewski, Mackenzie Q. Graham, Musa Musa, Alex D. Cocco, Ken D. Stark, Joe Quadrilatero, Robin E. Duncan   +10 more
wiley   +1 more source

Structure prediction analysis of human core TIM23 complex reveals conservation of the protein translocation mechanism

FEBS Open Bio
The majority of mitochondrial proteins are encoded in the nucleus, translated on cytosolic ribosomes, and subsequently targeted to the mitochondrial surface.
Klaudia K. Maruszczak, Piotr Draczkowski, Artur Wnorowski, Agnieszka Chacinska   +3 more
doaj   +1 more source

Mitochondrial Quality Control in Age-Related Pulmonary Fibrosis. [PDF]

, 2020
Idiopathic pulmonary fibrosis (IPF) is age-related interstitial lung disease of unknown etiology. About 100,000 people in the U.S have IPF, with a 3-year median life expectancy post-diagnosis.
Cuevas-Mora, Karina, Romero, Freddy, Roque, Willy   +2 more
core   +1 more source

The Yeast Aac2 Protein Exists in Physical Association with the Cytochrome \u3cem\u3ebc\u3c/em\u3e\u3csub\u3e1\u3c/sub\u3e-COX Supercomplex and the TIM23 Machinery [PDF]

, 2008
The ADP/ATP carrier (AAC) proteins play a central role in cellular metabolism as they facilitate the exchange of ADP and ATP across the mitochondrial inner membrane.
Dienhart, Mary Kathryn, Stuart, Rosemary A.   +1 more
core   +1 more source

Defining the core proteome of the chloroplast envelope membranes [PDF]

, 2013
High-throughput protein localization studies require multiple strategies. Mass spectrometric analysis of defined cellular fractions is one of the complementary approaches to a diverse array of cell biological methods. In recent years, the protein content
Ibrahim, Mohamed, Karas, Michael, Leisegang, Matthias, Mirus, Oliver, Müller, Bernd, Papasotiriou, Dimitrios, Schleiff, Enrico, Schorge, Tobias, Simm, Stefan, Sommer, Maik Sascha   +9 more
core   +2 more sources

SAT-347 Unfolding Generates an Active CYP11A1 for Mitochondrial Integration and Activity

Journal of the Endocrine Society, 2019
Mitochondrial protein import and sorting are mediated by translocases. Precursor proteins with amino-terminal presequences transition from the translocase of the outer membrane (TOM) complex to the translocase of the inner membrane (TIM) complex.
H. Bose, F. Gebrail, B. Marshall, Elizabeth Perru, R. Whittal   +4 more
semanticscholar   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine
Mitochondria are the foundation of cellular energy metabolism and are crucial for cell growth and development. Mitochondrial dysfunction can disrupt cellular energy metabolism and normal cellular functions, contributing to the onset of related diseases ...
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
doaj   +1 more source

OCIAD1 and prohibitins regulate the stability of the TIM23 protein translocase

Cell Reports
Summary: Mitochondrial proteins are transported and sorted to the matrix or inner mitochondrial membrane by the presequence translocase TIM23. In yeast, this essential and highly conserved machinery is composed of the core subunits Tim23 and Tim17.
Praveenraj Elancheliyan, Klaudia K. Maruszczak, Remigiusz Adam Serwa, Till Stephan, Ahmet Sadik Gulgec, Mayra A. Borrero-Landazabal, Sonia Ngati, Aleksandra Gosk, Stefan Jakobs, Michal Wasilewski, Agnieszka Chacinska   +10 more
doaj   +1 more source

Data supporting the involvement of the adenine nucleotide translocase conformation in opening the Tl+-induced permeability transition pore in Ca2+-loaded rat liver mitochondria

Data in Brief, 2016
There we made available information about the effects of the adenine nucleotide translocase (ANT) ‘c’ conformation fixers (phenylarsine oxide (PAO), tert-butylhydroperoxide (tBHP), and carboxyatractyloside) as well as thiol reagent (4,4 ...
Sergey M. Korotkov
doaj   +1 more source