Evolutionary conservation of dual Sec translocases in the cyanelles of
BMC Evolutionary Biology, 2008 Background Cyanelles, the peptidoglycan-armored plastids of glaucocystophytes, occupy a unique bridge position in between free-living cyanobacteria and chloroplasts.
Löffelhardt Wolfgang +2 more
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EMBO Molecular Medicine, 2021 Adenine nucleotide translocase‐1 (ANT1) is an ADP/ATP transporter protein located in the inner mitochondrial membrane. ANT1 is involved not only in the processes of ADP/ATP exchange but also in the composition of the mitochondrial membrane permeability ...
Lin Zhao +10 more
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Cell Reports, 2022 Summary: The presequence translocase (TIM23 complex) imports precursor proteins into the mitochondrial inner membrane and matrix. The presequence translocase-associated motor (PAM) provides a driving force for transport into the matrix.
Chantal Priesnitz +6 more
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ANT2-defective fibroblasts exhibit normal mitochondrial bioenergetics
Molecular Genetics and Metabolism Reports, 2015 Adenine nucleotide translocase 2 (ANT2) transports glycolytic ATP across the inner mitochondrial membrane. Patients with ANT2 deletion were recently reported. We aimed at characterizing mitochondrial functions in ANT2-defective fibroblasts.
Dolly Prabhu +7 more
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Purification of Mitochondrial Ribosomes with the Translocase Oxa1L from HEK Cells
Bio-Protocol, 2021 Mitochondrial ribosomes (mitoribosomes) perform protein synthesis inside mitochondria, the organelles responsible for energy conversion and adenosine triphosphate (ATP) production in eukaryotic cells.
Hanting Yang, Nirupa Desai
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Granzyme B enters the mitochondria in a Sam50-, Tim22- and mtHsp70-dependent manner to induce apoptosis [PDF]
, 2017 We have found that granzyme B (GB)-induced apoptosis also requires reactive oxygen species resulting from the alteration of mitochondrial complex I. How GB, which does not possess a mitochondrial targeting sequence, enter this organelle is unknown. We
Bassoy, Esen Yonca +7 more
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The Suppressor of AAC2 Lethality SAL1 Modulates Sensitivity of Heterologously Expressed Artemia ADP/ATP Carrier to Bongkrekate in Yeast [PDF]
, 2013 The ADP/ATP carrier protein (AAC) expressed in Artemia franciscana is refractory to bongkrekate. We generated two strains of Saccharomyces cerevisiae where AAC1 and AAC3 were inactivated and the AAC2 isoform was replaced with Artemia AAC containing a ...
A Keller +71 more
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Protein import-independent functions of Tic56, a component of the 1-MDa translocase at the inner chloroplast envelope membrane [PDF]
Plant Signaling & Behavior, 2017 Tic56 is an essential subunit of a 1-MDa protein complex at the inner chloroplast envelope membrane that comprises Tic100, Tic214 and the protein conducting channel protein Tic20-I. The complex was characterized as the "general protein import translocase" because mutants in either of its subunits have a severe growth phenotype and fail to assemble a ...
Birgit, Agne +2 more
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Mitochondrial function is required for secretion of DAF-28/insulin in C. elegans. [PDF]
PLoS ONE, 2011 While insulin signaling has been extensively studied in Caenorhabditis elegans in the context of ageing and stress response, less is known about the factors underlying the secretion of insulin ligands upstream of the insulin receptor.
Ola Billing, Gautam Kao, Peter Naredi
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Oxidative protein folding in the mitochondrial intermembrane space [PDF]
, 2010 Disulfide bond formation is a crucial step for oxidative folding and necessary for the acquisition of a protein's native conformation. Introduction of disulfide bonds is catalyzed in specialized subcellular compartments and requires the coordinated ...
Anfinsen CB +4 more
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