Results 71 to 80 of about 1,246,248 (385)

Polymer translocation through a nanopore under an applied external field [PDF]

open access: yes, 2006
We investigate the dynamics of polymer translocation through a nanopore under an externally applied field using the 2D fluctuating bond model with single-segment Monte Carlo moves.
Alberts B.   +9 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Whole‐Genome Analyses Reveal the Distinct Taxonomic Status of the Hainan Population of Endangered Rucervus eldii and Its Conservation Implications

open access: yesEvolutionary Applications
Eld's deer Rucervus eldii (McClelland, 1842) is an ungulate that lives in tropical lowland forests in several countries of Indochina and Hainan Island of China.
Chenqing Zheng   +9 more
doaj   +1 more source

DAX-1 Expression in Pediatric Rhabdomyosarcomas: Another Immunohistochemical Marker Useful in the Diagnosis of Translocation Positive Alveolar Rhabdomyosarcoma [PDF]

open access: yes, 2015
OBJECTIVES: The aim of this study was to investigate the expression of DAX-1 in a series of pediatric rhabdomyosarcomas (RMS) with known translocation and compare it to Ap2\u3b2, known to be selectively expressed in ARMS. DESIGN: We revised a series of
Alaggio, Rita   +10 more
core   +5 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Diurnal roosts and minimum home range defined by sleeping sites of a thin-spined porcupine Chaetomys subspinosus (Rodentia: Erethizontidae)

open access: yesZoologia (Curitiba), 2010
The thin-spined porcupine Chaetomys subspinosus (Olfers, 1818) is a species endemic to the extremely disturbed and fragmented Brazilian Atlantic forest. Little is known about its natural history. We analyzed the preferences of porcupine diurnal roost and
Marlon Zortéa, Bernardo F. A. de Brito
doaj   +1 more source

Maternal 2:18 chromosomal translocation manifesting as cause for developmental delay in a proband

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth, 2020
Developmental disabilities are a group of related chronic disorders of early onset and said to affect 5% to 10% children. Mental Retardation or intellectual disability has been redefined and replaced with Global developmental delay by WHO as the ...
Purushottam Rao Manvikar, Preeti Awari
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Improper Primate Release Fuels Interspecific Mating: Cases of Two Mixed‐Species Groups in Bangladesh

open access: yesEcology and Evolution
Wildlife trafficking has escalated in recent years, leading to a rise in animal rescues every year. In Bangladesh, increasing numbers of primates are being rescued from illegal trades and private collections.
Tanvir Ahmed   +12 more
doaj   +1 more source

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