Results 71 to 80 of about 999,565 (340)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Ethics of Assisted Evolution in Marine Conservation

Frontiers in Marine Science, 2019
Climate change is outpacing existing rates of evolution and adaptation for many marine organisms. Human societies are pushing hard to find new solutions to save and protect marine ecosystems, generating research on manipulating genetics of wild organisms
Karen Filbee-Dexter, Karen Filbee-Dexter, Anna Smajdor   +2 more
doaj   +1 more source

Translocation Dynamics with Attractive Nanopore-Polymer Interactions [PDF]

, 2008
Using Langevin dynamics simulations, we investigate the influence of polymer-pore interactions on the dynamics of biopolymer translocation through nanopores. We find that an attractive interaction can significantly change the translocation dynamics. This
Aniket Bhattacharya, Kaifu Luo, M. Doi, M. P. Allen, P. G. de Gennes, See-Chen Ying, Tapio Ala-Nissila, V. M. Stanford   +7 more
core   +3 more sources

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Uptake, Translocation, Toxicity, and Impact of Nanoparticles on Plant Physiological Processes

Plants
The application of nanotechnology in agriculture has increased rapidly. However, the fate and effects of various nanoparticles on the soil, plants, and humans are not fully understood.
Maduraimuthu Djanaguiraman, Veerappan Anbazhagan, Om Parkash Dhankher, P. V. Vara Prasad   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Assessment of Heavy Metals (Cr, Cu, Pb, and Zn) Bioaccumulation and Translocation by Erigeron canadensis L. in Polluted Soil

Pollutants
This work aims to assess the bioavailability and bioaccumulation of Cr, Cu, Pb, and Zn in the soil–plant system (Erigeron canadensis L.) in the zone of anthropogenic impact in Dnipro city, a significant industrial and economic centre of Ukraine. Sampling
Volodymyr Laptiev, Michelle Giltrap, Furong Tian, Nataliia Ryzhenko   +3 more
doaj   +1 more source

Polymer translocation induced by adsorption

, 1998
We study the translocation of a flexible polymer through a pore in a membrane induced by its adsorption on \trans side of the membrane. When temperature $T$ is higher than $T_c$, the adsorption-desorption transition temperature, attractive interaction ...
Park, Pyeong Jun, Sung, Wokyung
core   +2 more sources

Nucleotide specificity of the enzymatic and motile activities of dynein, kinesin, and heavy meromyosin. [PDF]

, 1991
The substrate specificities of dynein, kinesin, and myosin substrate turnover activity and cytoskeletal filament-driven translocation were examined using 15 ATP analogues.
Furusawa, K, Malik, F, Ohashi, S, Okuno, M, Shimizu, T, Toyoshima, YY, Vale, RD   +6 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source