Results 131 to 140 of about 4,885 (171)

Leucodepletion for transmissible spongiform encephalopathies

British Journal of Biomedical Science, 2004
Transmissible spongiform encephalopathies (TSEs) have been recognised around the world for many years. Creutzfeldt-Jakob disease (CJD), one of the human forms of TSE, has been studied widely and thus far has not proved a great threat to human health. The emergence of two new TSEs--bovine spongiform encephalopathy (BSE) in cattle and variant Creutzfeldt-
C, St Romaine, G, Hazlehurst, A P, Jewell   +2 more
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An overview of transmissible spongiform encephalopathies

Animal Health Research Reviews, 2004
AbstractTransmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative disorders of humans and animals associated with an accumulation of abnormal isoforms of prion protein (PrP) in nerve cells. The pathogenesis of TSEs involves conformational conversions of normal cellular PrP (PrPc) to abnormal isoforms of PrP (PrPSc). While the protein-
K, Takemura, M, Kahdre, D, Joseph, A, Yousef, S, Sreevatsan   +4 more
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Transmissible spongiform encephalopathies in ruminants

Veterinary Clinics of North America: Food Animal Practice, 2004
Transmissible spongiform encephalopathies (TSEs) have been observed in North American sheep, cervidae, and cattle. The causative agent of TSEs seems to be proteins that induce a conformational change in normal host proteins. Common clinical signs ofTSEs include chronic weight loss and deteriorating neurologic function.
Jeff W, Tyler, John R, Middleton
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Transmissible Spongiform Encephalopathies

Journal of Food Science, 2005
The Institute of Food Technologists has issued this Scientific Status Summary to update our knowledge of transmissible spongiform encephalopathies and provide an authoritative perspective on the surrounding regulatory and trade landscape.
Will Hueston, Cory M. Bryant
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Animal Transmissible Spongiform Encephalopathies and Genetics

Veterinary Research Communications, 2003
The genotype of the host plays a crucial role in the pathogenesis of transmissible spongiform encephalopathies (TSEs). In this respect, the most important factor is represented by the gene of the prion protein (PrP). The present work summarizes the currently available knowledge on the genetic basis of TSEs focusing, in particular, on sheep scrapie ...
AGRIMI U., CONTE M., MORELLI L., DI BARI M. A., DI GUARDO, Giovanni, LIGIOS C., ANTONUCCI G., AUFIERO G. M., POZZATO N., MUTINELLI F., NONNO R., VACCARI G.   +11 more
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The Other Transmissible Spongiform Encephalopathies

Reviews in the Neurosciences, 2005
Murine leukemia viruses may produce encephalopathies that have the same characteristics as those induced by infectious proteins or prions: neuronal loss, astrocytosis, and absence of inflammatory response. The pathogenic mechanism is still poorly understood but it seems that it involves the envelope proteins (Env), which may be misprocessed in the cell,
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Reflections on the Transmissible Spongiform Encephalopathies

Veterinary Pathology, 1999
Forty years ago scrapie of sheep and goats was the only known transmissible degenerative disease of the central nervous system. Yet even then its transmissibility was controversial; indeed, its very nature disputed. Nevertheless, at the time, scrapie was unique; no other disease like it had been recognized in man or animals.
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[Transmissible spongiform encephalopathies in animals].

Revista de neurologia, 2000
The transmissible spongiform encephalopathies affect several species of higher animals apart from man. Amongst these, undoubtedly the best known is that affecting cattle, since the association between consumption of beef and its derivatives and the appearance of a variant of Creutzfeldt-Jakob disease in humans has been established.This type of ...
Brun Torres, Alejandro, Castilla, Joaquín, Torres, Juan María   +2 more
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Transmissible Spongiform Encephalopathies

2015
Prion diseases, also termed transmissible spongiform encephalopathies (TSEs), are inevitably fatal neurodegenerative conditions which affect humans and a wide variety of animals. The most common form of prion disease in humans is sporadic Creutzfeldt-Jakob disease (sCJD).
Markus Glatzel, Adriano Aguzzi
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The transmissible spongiform encephalopathies

Revue Scientifique et Technique de l'OIE, 2003
Transmissible spongiform encephalopathies (TSEs) represent a group of neurodegenerative diseases characterised by a very long incubation period in regard to the life expectancy of the host species. The lesions are restricted to the central nervous system, although the pathogenesis of infection implies a primary replication step of TSE agents in the ...
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