Results 171 to 180 of about 6,019 (214)
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THE TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES

Annual Review of Medicine, 1995
▪ Abstract  The human transmissible spongiform encephalopathies (TSEs), or prion diseases, are a group of rapidly progressive disorders characterized by a spectrum of clinical abnormalities that include cognitive impairment, ataxia, myoclonus, and visual, pyramidal, and extrapyramidal signs. They share a spongiform (vacuolar) degeneration and variable
L G, Goldfarb, P, Brown
openaire   +2 more sources

Atypical Scrapie in a Swiss Goat and Implications for Transmissible Spongiform Encephalopathy Surveillance

open access: yesJournal of Veterinary Diagnostic Investigation, 2007
Different types of transmissible spongiform encephalopathies (TSEs) affect sheep and goats. In addition to the classical form of scrapie, both species are susceptible to experimental infections with the bovine spongiform encephalopathy (BSE) agent, and ...
Torsten Seuberlich   +2 more
exaly   +2 more sources

Transmissible Spongiform Encephalopathies

Biochemical and Biophysical Research Communications, 1998
Scrapie, bovine spongiform encephalopathy (BSE), and the Creutzfeldt-Jakob disease (CJD) belong to a group of lethal neurodegenerative disorders in mammals. Prion diseases or transmissible spongiform encephalopathies (TSEs) are characterized by the accumulation of an abnormal isoform (PrPSc) of the host-encoded cellular prion protein (PrPC) in the ...
S, Liemann, R, Glockshuber
openaire   +2 more sources

Transmissible spongiform encephalopathies

The Lancet, 2004
Nosologically, transmissible spongiform encephalopathies (TSE or prion diseases) should be grouped with other neurodegenerative disorders such as Alzheimer's and Parkinson's diseases, which are all caused by toxic gain of function of an aberrant form of a constitutively expressed protein.
Steven J, Collins   +2 more
openaire   +2 more sources

Spiroplasma spp. from transmissible spongiform encephalopathy brains or ticks induce spongiform encephalopathy in ruminants

open access: yesJournal of Medical Microbiology, 2007
Spiroplasma, small motile wall-less bacteria, are linked by molecular and serological studies to the transmissible spongiform encephalopathies (TSEs), which include scrapie in sheep, chronic wasting disease (CWD) in deer and Creutzfeldt-Jakob disease in ...
Frank O Bastian   +2 more
exaly   +3 more sources

Leucodepletion for transmissible spongiform encephalopathies

British Journal of Biomedical Science, 2004
Transmissible spongiform encephalopathies (TSEs) have been recognised around the world for many years. Creutzfeldt-Jakob disease (CJD), one of the human forms of TSE, has been studied widely and thus far has not proved a great threat to human health. The emergence of two new TSEs--bovine spongiform encephalopathy (BSE) in cattle and variant Creutzfeldt-
C, St Romaine   +2 more
openaire   +2 more sources

An overview of transmissible spongiform encephalopathies

Animal Health Research Reviews, 2004
AbstractTransmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative disorders of humans and animals associated with an accumulation of abnormal isoforms of prion protein (PrP) in nerve cells. The pathogenesis of TSEs involves conformational conversions of normal cellular PrP (PrPc) to abnormal isoforms of PrP (PrPSc). While the protein-
K, Takemura   +4 more
openaire   +2 more sources

Transmissible Spongiform Encephalopathies

Journal of Food Science, 2005
The Institute of Food Technologists has issued this Scientific Status Summary to update our knowledge of transmissible spongiform encephalopathies and provide an authoritative perspective on the surrounding regulatory and trade landscape.
Will Hueston, Cory M. Bryant
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Transmissible Spongiform Encephalopathies

2007
Protein folding and misfolding, relevance to disease and function / Massimi Stefani -- Alzheimer's disease / Charlotte E. Teunissen and Tischa M. van der Cammen -- Improving Cholinergic Transmission -- Cholinergic transmission and acetylcholine release enhancers / Pierre Francotte, Pascal de Tullio and Bernard Pirotte -- AChE and its inhibition / Jure ...
Geschwind, M. D., Legname, G.
openaire   +3 more sources

Transmissible spongiform encephalopathies in ruminants

Veterinary Clinics of North America: Food Animal Practice, 2004
Transmissible spongiform encephalopathies (TSEs) have been observed in North American sheep, cervidae, and cattle. The causative agent of TSEs seems to be proteins that induce a conformational change in normal host proteins. Common clinical signs ofTSEs include chronic weight loss and deteriorating neurologic function.
Jeff W, Tyler, John R, Middleton
openaire   +2 more sources

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