Results 181 to 190 of about 6,019 (214)

Animal Transmissible Spongiform Encephalopathies and Genetics

Veterinary Research Communications, 2003
The genotype of the host plays a crucial role in the pathogenesis of transmissible spongiform encephalopathies (TSEs). In this respect, the most important factor is represented by the gene of the prion protein (PrP). The present work summarizes the currently available knowledge on the genetic basis of TSEs focusing, in particular, on sheep scrapie ...
AGRIMI U., CONTE M., MORELLI L., DI BARI M. A., DI GUARDO, Giovanni, LIGIOS C., ANTONUCCI G., AUFIERO G. M., POZZATO N., MUTINELLI F., NONNO R., VACCARI G.   +11 more
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Reflections on the Transmissible Spongiform Encephalopathies

Veterinary Pathology, 1999
Forty years ago scrapie of sheep and goats was the only known transmissible degenerative disease of the central nervous system. Yet even then its transmissibility was controversial; indeed, its very nature disputed. Nevertheless, at the time, scrapie was unique; no other disease like it had been recognized in man or animals.
openaire   +2 more sources

The Other Transmissible Spongiform Encephalopathies

Reviews in the Neurosciences, 2005
Murine leukemia viruses may produce encephalopathies that have the same characteristics as those induced by infectious proteins or prions: neuronal loss, astrocytosis, and absence of inflammatory response. The pathogenic mechanism is still poorly understood but it seems that it involves the envelope proteins (Env), which may be misprocessed in the cell,
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Transmissible spongiform encephalopathy

Reviews in Medical Microbiology, 1998
Transmissible spongiform encephalopaties (TSE) are a group of rare fatal diseases of humans and animals. Prions, small infectious proteinaceous particles, are their supposed cause. Prusiner's theory (Nobel price 1997) proves that pathogenetically active prions are conformated physiological prions but problems of pathogenesis of TSE are still open. Most
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Transmissible Spongiform Encephalopathies

2015
Prion diseases, also termed transmissible spongiform encephalopathies (TSEs), are inevitably fatal neurodegenerative conditions which affect humans and a wide variety of animals. The most common form of prion disease in humans is sporadic Creutzfeldt-Jakob disease (sCJD).
Markus Glatzel, Adriano Aguzzi
openaire   +1 more source

The transmissible spongiform encephalopathies

Revue Scientifique et Technique de l'OIE, 2003
Transmissible spongiform encephalopathies (TSEs) represent a group of neurodegenerative diseases characterised by a very long incubation period in regard to the life expectancy of the host species. The lesions are restricted to the central nervous system, although the pathogenesis of infection implies a primary replication step of TSE agents in the ...
openaire   +3 more sources

The pathogenesis of transmissible spongiform encephalopathy: routes to the brain and the erection of therapeutic barricades

Cellular and Molecular Life Sciences, 2001
Brown P
exaly  

Transmissible Spongiform Encephalopathies

2011
  +4 more sources

Epidemic of transmissible spongiform encephalopathy in sheep and goats in Italy

Lancet, The, 1999
Umberto Agrimi, Franco Cardone, Maurizio Pocchiari   +2 more
exaly  

Transmissible Spongiform Encephalopathy: From Its Beginnings to Daniel Carleton Gajdusek

2023
Brown Paul
exaly