Results 201 to 210 of about 20,782 (249)

Leucodepletion for transmissible spongiform encephalopathies

British Journal of Biomedical Science, 2004
Transmissible spongiform encephalopathies (TSEs) have been recognised around the world for many years. Creutzfeldt-Jakob disease (CJD), one of the human forms of TSE, has been studied widely and thus far has not proved a great threat to human health. The emergence of two new TSEs--bovine spongiform encephalopathy (BSE) in cattle and variant Creutzfeldt-
C, St Romaine, G, Hazlehurst, A P, Jewell   +2 more
openaire   +2 more sources

Transmissible spongiform encephalopathies in ruminants

Veterinary Clinics of North America: Food Animal Practice, 2004
Transmissible spongiform encephalopathies (TSEs) have been observed in North American sheep, cervidae, and cattle. The causative agent of TSEs seems to be proteins that induce a conformational change in normal host proteins. Common clinical signs ofTSEs include chronic weight loss and deteriorating neurologic function.
Jeff W, Tyler, John R, Middleton
openaire   +2 more sources

Animal Transmissible Spongiform Encephalopathies and Genetics

Veterinary Research Communications, 2003
The genotype of the host plays a crucial role in the pathogenesis of transmissible spongiform encephalopathies (TSEs). In this respect, the most important factor is represented by the gene of the prion protein (PrP). The present work summarizes the currently available knowledge on the genetic basis of TSEs focusing, in particular, on sheep scrapie ...
AGRIMI U., CONTE M., MORELLI L., DI BARI M. A., DI GUARDO, Giovanni, LIGIOS C., ANTONUCCI G., AUFIERO G. M., POZZATO N., MUTINELLI F., NONNO R., VACCARI G.   +11 more
openaire   +3 more sources

A designer molecular chaperone against transmissible spongiform encephalopathy slows disease progression in mice and macaques

Nature Biomedical Engineering, 2019
Kei-ichi Yamaguchi, Y. Kamatari, F. Ono, H. Shibata, T. Fuse, Abdelazim Elsayed ELHELALY, Mayuko Fukuoka, Tsutomu Kimura, Junji Hosokawa-Muto, Takeshi Ishikawa, M. Tobiume, Yoshinori Takeuchi, Y. Matsuyama, D. Ishibashi, N. Nishida, K. Kuwata   +15 more
semanticscholar   +1 more source

The Other Transmissible Spongiform Encephalopathies

Reviews in the Neurosciences, 2005
Murine leukemia viruses may produce encephalopathies that have the same characteristics as those induced by infectious proteins or prions: neuronal loss, astrocytosis, and absence of inflammatory response. The pathogenic mechanism is still poorly understood but it seems that it involves the envelope proteins (Env), which may be misprocessed in the cell,
openaire   +2 more sources

Polymorphisms of the prion gene promoter region that influence classical bovine spongiform encephalopathy susceptibility are not applicable to other transmissible spongiform encephalopathies in cattle.

Journal of Animal Science, 2007
Brian W. Brunelle, Amirali N Hamir, T. Baron, A. Biacabe, Juergen A. Richt, R. Kunkle, R. Cutlip, Janice M. Miller, Eric M. Nicholson   +8 more
semanticscholar   +1 more source

Transmissible spongiform encephalopathies

2001
Abstract Unique among the neurodegenerative diseases, the spongiform encephalopathies are transmissi- ble, either experimentally or as a result of cannibalistic, iatrogenic, or zoonotic infections in humans. First described in the 1920s by Creutzfeldt and Jakob, whose names memorialize its most common form, human spongiform ...
openaire   +1 more source

Inactivation of transmissible spongiform encephalopathy agents in food products by ultra high pressure-temperature treatment.

Biochimica et Biophysica Acta, 2006
F. Cardone, P. Brown, R. Meyer, M. Pocchiari   +3 more
semanticscholar   +1 more source

TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHY IN THE 21st CENTURY: NEUROSCIENCE FOR THE CLINICAL NEUROLOGIST

Neurology, 2009
Steven R. Brenner
semanticscholar   +1 more source

High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein.

Journal of Mass Spectrometry, 2009
A. Gielbert, L. Davis, A. R. Sayers, J. Hope, A. Gill, M. Sauer   +5 more
semanticscholar   +1 more source