Results 41 to 50 of about 6,321,951 (301)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The inversed Preisach hysteresis model is widely used to realize the rapid coupling of hysteresis characteristics of core materials in finite element analysis. However, the small major hysteresis loop is difficult to be accurately simulated.
Long Chen +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Wildfires can threaten the safety of transmission towers by degrading galvanized coatings and reducing the load-bearing capacity of steel members exposed to elevated temperatures.
Haiwen Xu +4 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Influence of the line characterization on the transient analysis of nonlinearly loaded lossy transmission lines [PDF]
The analysis of nonlinearly terminated lossy transmission lines is addressed in this paper with a modified version of a method belonging to the class of mixed techniques, which characterize the line in the frequency domain and solve the nonlinear problem
PIGNARI, SERGIO AMEDEO +6 more
core +1 more source
An accurate analysis of the dynamic process of ice melting in an optical fiber composite overhead ground wire (OPGW) is of great reference significance for the selection of an ice melting current and the formulation of an ice melting strategy.
Shuang Wang +4 more
doaj +1 more source
A time-domain finite-element method for solving dynamic hysteretic magnetic fields under non-sinusoidal excitations [PDF]
Accurate iron loss calculation in electrical equipment under non-sinusoidal excitation necessitates stable finite element methods incorporating dynamic hysteresis properties.
Biao Huang +4 more
doaj +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source

