Results 51 to 60 of about 2,396,561 (291)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Optimal design scheme based on the segmental transmission line methodology for high-frequency interconnection in 3D micro/nano integration

Nanotechnology and Precision Engineering, 2020
With the continuous growth of signal frequency and package density, discontinuity of the high-frequency interconnection in 3D micro/nano integration becomes unavoidable, which results in serious signal integrity problems.
Chenye Li, Zhensong Li, Min Miao
doaj   +1 more source

Traveling Wave Parametric Amplifier based on a chain of Coupled Asymmetric SQUIDs

, 2015
A traveling wave parametric amplifier (TWPA) composed of a transmission line made up of a chain of coupled asymmetric superconducting quantum interference devices (SQUIDs) is proposed.
Bell, M. T., Samolov, A.
core   +1 more source

Polynomial Chaos-Based Tolerance Analysis of Microwave Planar Guiding Structures [PDF]

, 2011
This paper focuses on the derivation of an enhanced transmission-line model allowing to describe a realistic microwave interconnect with the inclusion of external uncertainties, like tolerances or process variations. The proposed method, that is based on
Canavero, Flavio, Manfredi, Paolo
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Modified Static Hysteresis Simulation Method for Electrical Equipment with Silicon Steel Core

Zhongguo dianli
Compared to traditional hysteresis models like Preisach and Jiles-Atherton (J-A), the micromagnetic Landau-Lifshitz-Gilbert (LLG) equation offers advantages such as clearer physical interpretation and higher simulation accuracy.
Ren LIU, Yu ZENG, Anlong HU, Bo TANG
doaj   +1 more source

A Review of Nonlinear Transmission Line System Design

IEEE Access, 2020
Nonlinear transmission lines (NLTLs) have been increasingly studied to produce high power microwaves (HPM) at higher repetition rates than conventional HPM devices without requiring the same auxiliary systems. The ability to array NLTLs to produce higher
Andrew J. Fairbanks, Adam M. Darr, Allen L. Garner   +2 more
doaj   +1 more source

Efficient transient simulation of transmission lines [PDF]

, 2002
The paper focuses on revealing the salient structural aspects of a new transmission-line model with a view to exploiting them for gains in efficiency and accuracy. The new transmission-line model has as its basis the Telegraphers Equations but the manner
Condon, Marissa
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

An Integrated Assessment Method for Power System Transient Stability Based on CBAM-ConvGRU [PDF]

Dianli jianshe
[Objective] To improve the effectiveness of transient stability assessment in power systems and address evaluation performance degradation under class-imbalance conditions，this paper proposes an integrated multi-task transient stability assessment method
XU Yanchun, SUN Sihan, ZHANG Jingyu, TANG Xinlin, ZHANG Tao, XI Lei, WANG Lingyun, MI Lu
doaj   +1 more source