Results 61 to 70 of about 2,396,561 (291)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Power Quality Estimation in a Remote Wind-Diesel Hybrid Power System in Cartwright, Labrador
Electrica, 2019 Generation of electricity using diesel is costly for small remote isolated communities. At remote location electricity generation from renewable energy such as wind can help reduce the overall operating costs by reducing the fuel costs.
Sheikh Mominul Islam, M. Tariq Iqbal
doaj +2 more sources
Integrated Mode Composite Transmission Line
IEEE Access, 2019 In this paper, a novel integrated mode composite transmission line (IMCTL) is proposed, which consists of inner and outer transmission lines. The proposed IMCTL takes full advantages of both substrate integrated waveguide (SIW) and spoof surface Plasmon ...
Sensong Shen +3 more
doaj +1 more source
Financial Transmission Rights (FTR) as a Congestion Management Scheme in Electricity Transmission: Strategic Behavior in a Coupled FTR — Electricity Market Model [PDF]
, 2015 With the emergence of liberalized markets, transmission line congestion has been a prominent technical constraint that has to be accounted for in designing the new markets.
Oruc, S.
core
Many Body Physics with Coupled Transmission Line Resonators
, 2012 We present the Josephson junction intersected superconducting transmission line resonator. In contrast to the Josephson parametric amplifier, Josephson bifurcation amplifier and Josephson parametric converter we consider the regime of few microwave ...
Hartmann, Michael J., Leib, Martin
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Attenuation correction for TOF-PET with a limited number of stationary coincidence line-sources [PDF]
, 2013 INTRODUCTION Accurate attenuation correction remains a major issue in combined PET/MRI. We have previously presented a method to derive the attenuation map by performing a transmission scan using an annulus-shaped source placed close to the edge of the ...
Karp, Joel +4 more
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