Results 21 to 30 of about 28,513 (235)

Diverse Routes of Allograft Tolerance Disruption by Memory T Cells

Frontiers in Immunology, 2020
Memory T lymphocytes constitute a significant problem in tissue and organ transplantation due their contribution to early rejection and their relative resistance to tolerance-promoting therapies.
Ronald G. Gill, Adam L. Burrack
doaj   +1 more source

Establishment of Etv5 gene knockout mice as a recipient model for spermatogonial stem cell transplantation

Biology Open, 2021
Spermatogonial stem cell (SSC) transplantation is an alternative reproductive method to achieve conservation and production of elite animals in livestock production. Creating a recipient animal without endogenous germ cells is important for effective SSC
Xianyu Zhang, Xin Zhao, Guoling Li, Mao Zhang, Pingping Xing, Zicong Li, Bin Chen, Huaqiang Yang, Zhenfang Wu   +8 more
doaj   +1 more source

Potential of Adipose-derived stem cells in muscular regenerative therapies

Frontiers in Aging Neuroscience, 2015
Regenerative capacity of skeletal muscles resides in satellite cells, a self-renewing population of muscle cells. Several studies are investigating epigenetic mechanisms that control myogenic proliferation and differentiation to find new approaches that ...
Sonia eForcales
doaj   +1 more source

Establishment and resilience of transplanted gut microbiota in aged mice

iScience, 2022
Summary: The maintenance of healthy and resilient gut microbiota is critical for the life quality and healthspan of the elderly. Fecal microbiota transplantation (FMT) has been increasingly used to restore healthy gut microbiota.
Ying Wang, Jinhui Tang, Qingqing Lv, Yuxiang Tan, Xiaoxiao Dong, Hongbin Liu, Nannan Zhao, Zhen He, Yan Kou, Yan Tan, Xin-an Liu, Liping Wang, Yang-Yu Liu, Lei Dai   +13 more
doaj  

Surgical Options for Aortic Root Replacement in Destructive Endocarditis

Brazilian Journal of Cardiovascular Surgery
Objective: To analyze patients’ preoperative characteristics, surgical data, postoperative courses, and short- and long-term outcomes after implantation of different full-root prostheses for destructive aortic valve endocarditis.
Marcin Szczechowicz, Alexander Weymann, Sabreen Mkalaluh, Ahmed Mashhour, Konstantin Zhigalov, Jerry Easo   +5 more
doaj   +1 more source

T Cell Repertoire Maturation Induced by Persistent and Latent Viral Infection Is Insufficient to Induce Costimulation Blockade Resistant Organ Allograft Rejection in Mice

Frontiers in Immunology, 2018
CD28:CD80/86 pathway costimulation blockade (CoB) with the CD80/86-specific fusion protein CTLA4-Ig prevents T cell-mediated allograft rejection in mice.
Jaclyn R. Espinosa, Jaclyn R. Espinosa, Danny Mou, Bartley W. Adams, Louis R. DiBernardo, Andrea L. MacDonald, MacKenzie McRae, Allison N. Miller, Mingqing Song, Linda L. Stempora, Jun Wang, Neal N. Iwakoshi, Allan D. Kirk   +12 more
doaj   +1 more source

Combination of heterologous fibrin sealant and bioengineered human embryonic stem cells to improve regeneration following autogenous sciatic nerve grafting repair

Journal of Venomous Animals and Toxins including Tropical Diseases, 2018
Background Peripheral nerve injury is a worldwide clinical problem, and the preferred surgical method for treating it is the end-to-end neurorrhaphy. When it is not possible due to a large nerve gap, autologous nerve grafting is used.
Roghayeh Mozafari, Sergiy Kyrylenko, Mateus Vidigal Castro, Rui Seabra Ferreira, Benedito Barraviera, Alexandre Leite Rodrigues Oliveira   +5 more
doaj   +1 more source

Induced Foxp3+ T cells colonising tolerated allografts exhibit the hypomethylation pattern typical of mature regulatory T cells.

Frontiers in Immunology, 2016
Regulatory T cells expressing the transcription factor Foxp3 require acquisition of a specific hypomethylation pattern to ensure optimal functional commitment, limited lineage plasticity and long-term maintenance of tolerance.
Robert eHilbrands, Ye eChen, Adrian eKendal, Elizabeth eAdams, Stephen Paul Cobbold, Herman eWaldmann, Duncan eHowie   +6 more
doaj   +1 more source

Cellular and Humoral SARS-CoV-2 Vaccination Responses in 192 Adult Recipients of Allogeneic Hematopoietic Cell Transplantation

Vaccines, 2022
To determine factors influencing the vaccination response against SARS-CoV-2 is of importance in recipients of allogeneic hematopoietic cell transplantation (allo-HCT) as they display an increased mortality after SARS-CoV-2 infection, an increased risk ...
Thomas Meyer, Gabriele Ihorst, Ingrid Bartsch, Robert Zeiser, Ralph Wäsch, Hartmut Bertz, Jürgen Finke, Daniela Huzly, Claudia Wehr   +8 more
doaj   +1 more source

Modification of established rejection of canine kidney and liver homografts with antilymphocyte gamma-G globulin [PDF]

, 1969
Heterologous ALG was administered to ten canine recipients of renal homografts and one recipient of an orthotopic liver. Treatment was started after rejection was well established.
Kashiwagi, N, Kolff, J, Putnam, CW, Smith, GV, Starzl, TE   +4 more
core