Results 121 to 130 of about 1,247,898 (402)

Islet cell replacement and transplantation immunology in a mouse strain with inducible diabetes. [PDF]

Sci Rep, 2022
Bhagchandani P, Chang CA, Zhao W, Ghila L, Herrera PL, Chera S, Kim SK.   +6 more
europepmc   +1 more source

Use of the methylxanthine derivative A802715 in transplantation immunology: I. Strong in vitro inhibitory effects on CD28-costimulated T cell activities.

Transplantation, 1997
BACKGROUND Recently, methylxanthines such as pentoxifylline (PTX) were shown to be immunosuppressive in vitro. Unfortunately, when used in transplant patients, PTX was poorly active as an immunosuppressant.
Y. Lin, J. Goebels, O. Rutgeerts, A. Kasran, S. V. Van Gool, J. Ceuppens, M. Schönharting, M. Waer   +7 more
semanticscholar   +1 more source

Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population

Advanced Science, EarlyView.
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen, Lizhi Guan, Chao Wu, Yiwen Gong, Lei Wu, Minchun Zhang, Zhiwen Cao, Yufei Chen, Chengcan Yang, Bing Wang, Yunqi Li, Bin Li, Yufang Bi, Guang Ning, Jiqiu Wang, Weiqing Wang, Ruixin Liu   +16 more
wiley   +1 more source

Gene Expression Profiling of Bronchoalveolar Lavage Cells Preceding a Clinical Diagnosis of Chronic Lung Allograft Dysfunction. [PDF]

, 2017
BackgroundChronic Lung Allograft Dysfunction (CLAD) is the main limitation to long-term survival after lung transplantation. Although CLAD is usually not responsive to treatment, earlier identification may improve treatment prospects.MethodsIn a nested ...
Ardehali, Abbas, Belperio, John A, Birjandi, Shirin, DerHovanessian, Ariss, Elashoff, David, Gregson, Aric L, Lynch, Joseph P, Palchevskiy, Vyacheslav, Palmer, Scott M, Patel, Naman, Ross, David J, Saggar, Rajan, Sayah, David M, Shino, Michael Y, Wang, Xiaoyan, Weigt, S Samuel   +15 more
core   +2 more sources

Intestinal Transplant Immunology and Intestinal Graft Rejection: From Basic Mechanisms to Potential Biomarkers [PDF]

, 2023
Martı́n Rumbo, Mihai Oltean
openalex   +1 more source

Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis

Advanced Science, EarlyView.
VPS72 overexpression activates mTORC1 signaling, subsequently promoting lipid synthesis and driving HCC progression. VPS72 modulates the epigenetic landscape of ATF3 promoter, such as H2A.Z acetylation reduction and DNA methylation increase, which results in ATF3 repression and subsequent activation of mTORC1.
Qinglin Zhang, Yunxing Huang, Yin Tong, Kenneth Tsz Chun Ng, Jiangwen Zhang   +4 more
wiley   +1 more source

G6PD deficiency in patients identified as female

, 2023
American Journal of Hematology, Volume 98, Issue 2, Page 359-360, February 2023.
Barbara J. Bain, Jane Myburgh, Kirstin Lund, Aristeidis Chaidos   +3 more
wiley   +1 more source

Equal Expansion of Endogenous Transplant-Specific Regulatory T Cell and Recruitment Into the Allograft During Rejection and Tolerance

Frontiers in Immunology, 2018
Despite numerous advances in the definition of a role for regulatory T cells (Tregs) in facilitating experimental transplantation tolerance, and ongoing clinical trials for Treg-based therapies, critical issues related to the optimum dosage, antigen ...
James S. Young, Dengping Yin, Augustin Georges Louis Vannier, Maria-Luisa Alegre, Anita S. Chong   +4 more
doaj   +1 more source

Determining the Quantitative Principles of T Cell Response to Antigenic Disparity in Stem Cell Transplantation [PDF]

, 2018
Alloreactivity compromising clinical outcomes in stem cell transplantation is observed despite HLA matching of donors and recipients. This has its origin in the variation between the exomes of the two, which provides the basis for minor ...
AbdulRazzaq, Badar, Buck, Greg, Hall, Charles E., Hashmi, Shahrukh, Jameson-Lee, Max, Kennedy, Caleb, Koparde, Vishal, Manjili, Masoud H., Meier, Jeremy, Neale, Michael, Qayyum, Rehan, Reed, Jason, Roberts, Catherine, Salman, Ali, Serrano, Myrna, Spellman, Stephen R., Toor, Amir A., Wijesinghe, Dayanjan   +17 more
core   +1 more source

The immunology of corneal limbal stem cells: the up-to-date approach to stem cell transplantation [PDF]

, 2023
Katarzyna Samelska, Magdalena Kupis, Katarzyna Szymanek, Justyna Izdebska, Anna Zaleska-Żmijewska, Piotr Skopiński   +5 more
openalex   +1 more source