Transplante de córnea na infância [PDF]
, 2012 Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Felicissimo, Lucas Costa
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
RELATO DE CASO: LEUCEMIA MIELOIDE AGUDA COM PRESENÇA NECROSE DE MEDULA ÓSSEA AO DIAGNÓSTICO
Hematology, Transfusion and Cell TherapyIntrodução: A leucemia mieloide aguda (LMA) é uma neoplasia hematológica caracterizada pela proliferação clonal de células progenitoras mieloides. As mutações nos genes FLT3 e NPM1 são comuns na LMA e estão associadas a um prognóstico variado. A presença
DSC Filho +9 more
doaj +1 more source
Aspectos jurídico-penais e bioéticos acerca da mercancia de órgãos humanos provenientes de indivíduos vivos [PDF]
, 2007 The present Dissertation was performed within research line called “Criminal Politics, State and Limitation of the Punishment”, in the concentration area of “Violence”, of the Post Graduation Program in Criminal Sciences of the Pontifícia Universidade ...
Bueno, Marisa Fernanda da Silva
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Lo viejo y lo nuevo. Una aproximación antropológica a los cambios socioculturales en las personas transplantadas [PDF]
, 2005 El transplante de órganos y tejidos se realiza en nuestra sociedad, a través de la donación, el altruismo y la solidaridad de los donantes. El presente artículo, fruto de una investigación en curso, parte del análisis en profundidad de las entrevistas ...
Venturas Nieto, Montserrat
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Análise do perfil sorológico de potenciais doadores de órgãos sólidos em Santa Catarina. [PDF]
, 2008 Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Amaral, Robson Pereira do
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Partially matched family donor allogeneic bone marrow transplantation [PDF]
, 2010 O transplante de células-tronco hematopoéticas alogênico (TCTH alo) após um regime de condicionamento ablativo ou não mieloablativo é um tratamento potencialmente curativo para uma grande variedade de doenças malignas hematológicas e outras desordens não
DULLEY, Frederico L. +3 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source