Results 81 to 90 of about 10,653 (287)

Causal transportability of experiments on controllable subsets of variables: Z-transportability

open access: yes, 2013
We introduce z-transportability, the problem of estimating the causal effect of a set of variables X on another set of variables Y in a target domain from experiments on any subset of controllable variables Z where Z is an arbitrary subset of observable ...
Lee, Sanghack, Honavar, Vasant
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Research of calcium oxide hydration in calcium nitrate solutions

open access: yesTrudy Odesskogo Politehničeskogo Universiteta, 2016
Mineral fertilizers are one of the important factors of agriculture intensification and increasing of food products quantity. The volume of fertilizers production and its domestic consumption in Ukraine indicate that nitrogen fertilizer using only comes
Микола Андрійович Олійник   +1 more
doaj   +5 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A Weighted Resampling Framework for Causal Transportability

open access: yes
Transferring well-studied causal knowledge to new environments and populations can accelerate scientific advancement by enabling reusable findings, i.e., the causal transportability.
Mao, Jianqiao; id_orcid, Little, Max
core   +4 more sources

Additive Effect of Dornase Alfa and Nacystelyn on Transportability and Viscoelasticity of Cystic Fibrosis Sputum

open access: yesCanadian Respiratory Journal, 2002
OBJECTIVE: To investigate the effect of dornase alfa (DA), Nacystelyn (NAL) and their combination on mucociliary transportability and mucus viscoelasticity of cystic fibrosis (CF) sputum, and to assess whether the combination possesses an additive effect.
Feng Sun   +4 more
doaj   +1 more source

Transportability across studies: A formal approach [PDF]

open access: yes, 2011
We provide a formal definition of the notion of “transportability,” or “external validity,” which we view as a license to transfer causal information learned in experimental studies to a different environment, in which only observational studies can be ...
Pearl, Judea
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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