Results 71 to 80 of about 1,006,093 (289)

Engaging Undergraduate Students in Transportation Studies through Simulating Transportation for Realistic Engineering Education and Training (STREET) [PDF]

open access: yes
The practice of transportation engineering and planning has evolved substantially over the past several decades. A new paradigm for transportation engineering education is required to better engage students and deliver knowledge.
Chen-Fu Liao, David Levinson, Henry Liu
core  

'Resilience thinking' in transport planning [PDF]

open access: yes, 2015
Resilience has been discussed in ecology for over forty years. While some aspects of resilience have received attention in transport planning, there is no unified definition of resilience in transportation. To define resilience in transportation, I trace
Holling C. S.   +4 more
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Demand responsive transit scheduling method considering passenger travel choice

open access: yesShenzhen Daxue xuebao. Ligong ban
Demand responsive transit service faces the challenge of maintaining operating profits while complying with passenger preferences. To address this, a multinomial logit model was established to describe passenger travel choice behaviors, and a service ...
SUN Jie, JIN Wenzhou, ZHANG Yong
doaj   +1 more source

Space shuttle electrical power generation and reactant supply system [PDF]

open access: yes, 1985
The design philosophy and development experience of fuel cell power generation and cryogenic reactant supply systems are reviewed, beginning with the state of technology at the conclusion of the Apollo Program. Technology advancements span a period of 10
Simon, W. E.
core   +1 more source

Pseudo-solidification of dredged marine soils with cement - fly ash for reuse in coastal development [PDF]

open access: yes, 2015
The dislodged and removed sediments from the seabed, termed dredged marine soils, are generally classified as a waste material requiring special disposal procedures.
Chee, Shen Lim   +8 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Highway "Firsts" - State of Iowa, 1971 [PDF]

open access: yes, 1971
Brief summaries of achievement and important events of the Iowa State Highway Commission and transportation engineering in Iowa, between 1904 and ...

core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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