Results 221 to 230 of about 100,531 (319)

The epigenomic landscape of transposable elements across normal human development and anatomy [PDF]

, 2019
Choudhary, Mayank N.K., Pehrsson, Erica C., Sundaram, Vasavi, Wang, Ting   +3 more
core   +1 more source

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

High transposable element expression in sarcomas is associated with increased immune infiltrates and improved outcomes including after immunotherapy. [PDF]

J Immunother Cancer
Nacev BA, Bradic M, Woo HJ, Richards AL, Kelly CM, Dickson MA, Gounder MM, Keohan ML, Chi P, Movva S, Maki RG, Slotkin EK, Rosenbaum E, Avutu V, Chan JE, Banks LB, Adamson T, Singer S, Antonescu CR, Tap WD, Donoghue MT, D'Angelo SP.   +21 more
europepmc   +1 more source

Jordan, an active Volvox transposable element similar to higher plant transposons. [PDF]

, 1993
Allison J. Miller, R. Schmitt, David Kirk   +2 more
openalex   +1 more source

Ythdc1‐p300‐Klf5 Complex‐Mediated Golgi Dysfunction Promotes Aortic Aneurysm

Advanced Science, EarlyView.
In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wen‐Li Wang, Zhi‐Xue Song, Si‐Ming Bu, Yi‐Mei Liu, Qing Li, Wen‐Xia Zhang, Xu‐Rong Sun, Xin Zhang, Yu‐Xuan Xiao, Di Bo, Xu‐Bin Miao, Chao Liu, Xin‐Hua Zhang, Lei Zheng, Hong‐Ye Zhao, Bao‐Lian Zhang, Wen Jia, Kui Chi, Yu Liu, Yong‐Bo Zhao, Bin Zheng, Dong Ma, Jin‐Kun Wen   +22 more
wiley   +1 more source

Nature‐Inspired Innovation in Electrical Engineering Technologies and Applications

Advanced Science, EarlyView.
This review investigates how nature‐inspired design principles revolutionize electrical engineering by translating biological mechanisms, such as sensing, actuation, energy conversion, and neural processing, into advanced intelligent technologies. Through interdisciplinary integration, biomimetic strategies enable efficient, adaptive, and sustainable ...
Ming Li, Anran Mao, Qingwen Guan, Yang Xu, Chang Li, Gang Lu, Eduardo Saiz   +6 more
wiley   +1 more source

Spatiotemporal Tracking of Three Novel Transposable Element Invasions in Drosophila melanogaster over the Last 30 Years. [PDF]

Mol Biol Evol
Pianezza R, Scarpa A, Haider A, Signor S, Kofler R.   +4 more
europepmc   +1 more source

Leveraging 3D Molecular Spatial Visual Information and Multi‐Perspective Representations for Drug Discovery

Advanced Science, EarlyView.
A deep learning framework called MolVisGNN is proposed to fuse 3D molecular visual information of drugs with multi‐source features, which proves the importance of 3D molecular visual information of drugs and the advancedness of this model in the field of drug discovery, and provides a reference for how to more comprehensively express small molecule ...
Zimai Zhang, Xi Zhou, Yujie Qi, Xiaobo Zhu, Xun Deng, Feng Tan, Yuan Huang, Lun Hu, Zhuhong You, Pengwei Hu   +9 more
wiley   +1 more source

Transposable element dynamics in Xenopus laevis embryogenesis: a tale of two coexisting subgenomes. [PDF]

Mob DNA
Tittarelli E, Carotti E, Carducci F, Barucca M, Canapa A, Biscotti MA.   +5 more
europepmc   +1 more source

Population dynamics of Herves transposable element in Anopheles gambiae [PDF]

, 2005
Aluvihare, C, Atkinson, P, Charlwood, D, Curtis, C, Meeraus, W, O'Brochta, DA, Peckham, E, Subramanian, RA   +7 more
core