Results 61 to 70 of about 116,997 (341)
Enrichment analysis of Alu elements with different spatial chromatin proximity in the human genome [PDF]
, 2016 Transposable elements (TEs) have no longer been totally considered as “junk DNA” for quite a time since the continual discoveries of their multifunctional roles in eukaryote genomes.A Antonaki, A Huda, A Nekrutenko, A Smallwood, AF Smit, AM Deaton, C Esnault, C Feschotte, CB Lowe, CT Ong, D Grover, D Grover, D Schmidt, D Xie, E Berezikov, E Lieberman-Aiden, E Wit de, E Yaffe, EP Nora, ES Lander, ES Lander, F Cui, G Bourque, G Kunarso, G Li, G Li, GA Maston, GJ Faulkner, GN Gallus, H Santos-Rosa, H Santos-Rosa, H Xie, HH Kazazian Jr, IK Jordan, J Banerji, J Dekker, J Dostie, J Jurka, J Jurka, J Ule, JA Yoder, JE Hambor, JF Brookfield, JF Brookfield, JM Chen, JR Dixon, JR Korenberg, K Ahn, K Kaer, KC Wang, L Lin, L Teng, M Hackenberg, M Simonis, M Weber, MA Batzer, MG Kidwell, MH Kagey, MJ Fullwood, MM Suzuki, ND Heintzman, NR Smalheiser, P Jin, P Medstrand, P Polak, R Cordaux, R Eskeland, R Lister, R Schneider, R Sorek, RD Hawkins, S Shen, S Winkler, SD Gillies, SL Oei, T Pastor, T Wicker, V Kapitonov, VJ Lynch, WD Gifford, Y Lu, Y Quentin, Y Quentin, Y Zhang +83 morecore +4 more sourcesVisual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini +12 morewiley +1 more sourceOccurrence of LINE, gypsy-like, and copia-like retrotransposons in the clonally propagated sweet potato (Ipomoea batatas L.) [PDF]
, 2011 Retrotransposons are a class of transposable elements that represent a major fraction of the repetitive DNA of most eukaryotes. Their abundance stems from their expansive replication strategies.Dieters, Mark, Godwin, Ian, Harding, Rob, Okpul, Tom +3 morecore +2 more sourcesLesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca +7 morewiley +1 more sourceDynamic Patterns of Transcript Abundance of Transposable Element Families in Maize. [PDF]
, 2019 Transposable Elements (TEs) are mobile elements that contribute the majority of DNA sequences in the maize genome. Due to their repetitive nature, genomic studies of TEs are complicated by the difficulty of properly attributing multi-mapped short reads ...Anderson, Sarah N, Hirsch, Cory D, Ross-Ibarra, Jeffrey, Springer, Nathan M, Stitzer, Michelle C, Zhou, Peng +5 morecore The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Aim
Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul +5 morewiley +1 more sourceThe genomes of two key bumblebee species with primitive eusocial organization [PDF]
, 2015 Background: The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies.Amdam, Gro V., Antonio, David S. Marco, Aqrawi, Peshtewani K., Asher, Claire, Barribeau, Seth M., Beckers, Matthew, Bennett, Anna K., Beye, Martin, Biewer, Matthias, Bitondi, Márcia M. G., Blankenburg, Kerstin P., Blaxter, Mark L., Bloch, Guy, Blommaert, Julie, Bornberg-Bauer, Erich, Bourke, Andrew F. G., Brown, Mark J. F., Buechel, Severine D., Cameron, Rossanah, Cappelle, Kaat, Carolan, James C., Chipman, Ariel D., Chittka, Lars, Christiaens, Olivier, Ciborowski, Kate L., Clarke, David F., Colgan, Thomas J., Collins, David H., Coyle, Marcus, Cridge, Andrew G., Câmara, Francisco, Dalmay, Tamas, de Graaf, Dirk C., Dearden, Peter, Debyser, Griet, Devreese, Bart, Dreier, Stephanie, du Plessis, Louis, Duncan, Elizabeth, Elsik, Christine G., Erler, Silvio, Evans, Jay, Falcon, Tiago, Flores, Kevin, Fouks, Bertrand, Francisco, Liezl, Freitas, Flávia C. P., Fuchikawa, Taro, Gadau, Jürgen, Gempe, Tanja, Gibbs, Richard A., Grimmelikhuijzen, Cornelis J. P., Guigó, Roderic, Hartfelder, Klaus, Hasselmann, Martin, Hauser, Frank, Helbing, Sophie, Hernandez, Alvaro G., Hoff, Katharina, Holder, Michael, Hudson, Matthew E., Humann, Fernanda C., Irvine, Frano, Jackson, Laronda, Jayaseelan, Joy, Jermiin, Lars S., Johnson, Claire E., Johnson, Reed M., Jones, Andrew K., Joshi, Vandita, Kadowaki, Tatsuhiko, Kidner, Jonathan H., Klasberg, Steffen, Koch, Vasco, Kovar, Christie, Kraus, F Bernhard, Köhler, Arian, Lattorff, H. Michael G., Leask, Megan, Lee, Sandra L., Liu, Jisheng, Lockett, Gabrielle A., Lozier, Jeffrey D., Mallon, Eamonn B., Mariotti, Marco, Marxer, Monika, Mata, Robert, Mathew, Tittu, Meeus, Ivan, Moritz, Robin F. A., Munoz-Torres, Monica, Murphy, Terence, Muzny, Donna M., Nair, Ajay, Newsham, Irene F., Ngo, Robin, Nissen, Inga, Niu, Jinzhi, Nunes, Francis M. F., Näpflin, Kathrin, O'Neill, Meaghan P., Oakeshott, John G., Okwuonu, Geoffrey, Osborne, Amy, Otte, Marianne, Pham, Christopher, Pinheiro, Daniel G., Pu, Ling-Ling, Puiu, Daniela, Qu, Jiaxin, Richards, Stephen, Robertson, Hugh M., Robinson, Gene E., Rossié, Nina, Rueppell, Olav, Saada, Nehad, Sadd, Ben M., Salzberg, Steven L., Santesmasses, Didac, Santibanez, Jireh, Santos, Carolina G., Scherer, Steven E., Schmid-Hempel, Paul, Schmid-Hempel, Regula, Schmitt, Björn D., Schulte, Christina, Simmons, Denard, Simões, Zilá Lp, Smagghe, Guy, Soares, Michelle P. M., Stolle, Eckart, Sumner, Seirian, Swevers, Luc, Thornton, Rebecca, van Vaerenbergh, Matthias, Venkat, Aarti, Walden, Kimberly K. O., Waterhouse, Robert M., Winnebeck, Eva C., Wolschin, Florian, Worley, Kim C., Wu, Yuan-Qing, Yu, Na, Zdobnov, Evgeny M. +143 morecore +16 more sourcesNetwork Localization of Fatigue in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background
Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa +12 morewiley +1 more source