Results 51 to 60 of about 149,269 (182)

Testicular expression of TDRD1, TDRD5, TDRD9 and TDRD12 in azoospermia. [PDF]

, 2020
BACKGROUND: Tudor domain-containing proteins (TDRDs) play a critical role in piRNA biogenesis and germ cell development. piRNAs, small regulatory RNAs, act by silencing of transposons during germline development and it has recently been shown in animal ...
Aghaei, M, Alipourfard, I, Babakhanzadeh, E, Ghasemi, N, Hosseinnia, M, Jamshidi, Y, Khodadadian, A, Mehrjardi, MYV, Nazari, M, Rostami, S   +9 more
core   +1 more source

A Naturally Active Spy Transposon Discovered from the Insect Genome of Colletes gigas as a Promising Novel Gene Transfer Tool

Advanced Science
Novel active DNA transposons, such as Spy transposons from the PHIS superfamily, are identified through bioinformatics in this study. The native transposases cgSpy and cvSpy displayed transposition activities of approximately 85% and 35% compared to the ...
Mohamed Diaby, Han Wu, Bo Gao, Shasha Shi, Bingqing Wang, Saisai Wang, Yali Wang, Zherui Wu, Cai Chen, Xiaoyan Wang, Chengyi Song   +10 more
doaj   +1 more source

The Integration Preference of Sleeping Beauty at Non-TA Site Is Related to the Transposon End Sequences

Frontiers in Genetics, 2021
Recently, we proved that Sleeping Beauty (SB) transposon integrates into non-TA sites at a lower frequency. Here, we performed a further study on the non-TA integration of SB and showed that (1) SB can integrate into non-TA sites in HEK293T cells as well
Yiting Zhou, Guangwei Ma, Jiawen Yang, Zenghong Gao, Yabin Guo   +4 more
doaj   +1 more source

Human Transposon Tectonics [PDF]

Cell, 2012
Mobile DNAs have had a central role in shaping our genome. More than half of our DNA is comprised of interspersed repeats resulting from replicative copy and paste events of retrotransposons. Although most are fixed, incapable of templating new copies, there are important exceptions to retrotransposon quiescence.
Burns, Kathleen H., Boeke, Jef D.
openaire   +2 more sources

Higher yields of cyclodepsipetides from Scopulariopsis brevicaulis by random mutagenesis [PDF]

, 2013
The ascomycete Scopulariopsis brevicaulis, which was isolated from the marine sponge Tethya aurantium, produces two cyclodepsipeptides, scopularides A and B [1]. Both peptides exhibit activity against several tumor cell lines.
Hihlal, ElKbir, Imhoff, Johannes F., Kempken, Frank, Kramer, Annemarie, Labes, Antje, Paun, Linda   +5 more
core  

Transposon variants and their effects on gene expression in arabidopsis [PDF]

, 2013
Transposable elements (TEs) make up the majority of many plant genomes. Their transcription and transposition is controlled through siRNAs and epigenetic marks including DNA methylation.
Smith, L.M., Wang, X., Weigel, D.
core   +3 more sources

Activity of Genes with Functions in Human Williams-Beuren Syndrome Is Impacted by Mobile Element Insertions in the Gray Wolf Genome. [PDF]

, 2018
In canines, transposon dynamics have been associated with a hyper-social behavioral syndrome, although the functional mechanism has yet to be described.
Aardema, Matthew L, Ji, Sarah S, Sinsheimer, Janet S, Stahler, Daniel R, Udell, Monique AR, vonHoldt, Bridgett M   +5 more
core   +2 more sources

Chromosomal DNA deletion confers phage resistance to Pseudomonas aeruginosa. [PDF]

, 2014
Bacteria develop a broad range of phage resistance mechanisms, such as prevention of phage adsorption and CRISPR/Cas system, to survive phage predation.
He, Xuesong, Hu, Fuquan, Jin, Xiaolin, Le, Shuai, Li, Ming, Lu, Shuguang, Lux, Renate, Rao, Xiancai, Shi, Wenyuan, Tan, Yinling, Wang, Jing, Wu, Nicholas C, Yao, Xinyue, Zhao, Yan   +13 more
core   +1 more source

Molecular characteristics and comparative genomics analysis of a clinical Enterococcus casseliflavus with a resistance plasmid

Infection and Drug Resistance, 2018
Min Yin,1,* Yi Jiang,1,* Changrui Qian,1 Fei Wu,1 Yuanyuan Ying,1 Chongyang Wu,1 Peizhen Li,1 Jun Ying,1 Kewei Li,1 Teng Xu,1 Qiyu Bao,1 Caixia Sun2 1Department of Microbiology and Immunology, School of Laboratory Medicine and Life Sciences/Institute of ...
Yin M, Jiang Y, Qian C, Wu F, Ying Y, Wu C, Li P, Ying J, Li K, Xu T, Bao Q, Sun C   +11 more
doaj  

Global Spread of Multiple Aminoglycoside Resistance Genes

Emerging Infectious Diseases, 2005
Emergence of the newly identified 16S rRNA methylases RmtA, RmtB, and ArmA in pathogenic gram-negative bacilli has been a growing concern. ArmA, which had been identified exclusively in Europe, was also found in several gram-negative pathogenic bacilli ...
Kunikazu Yamane, Jun-ichi Wachino, Yohei Doi, Hiroshi Kurokawa, Yoshichika Arakawa   +4 more
doaj   +1 more source