Results 61 to 70 of about 149,269 (182)

Insights into a Novel blaKPC-2-Encoding IncP-6 Plasmid Reveal Carbapenem-Resistance Circulation in Several Enterobacteriaceae Species from Wastewater and a Hospital Source in Spain [PDF]

, 2017
Untreated wastewater, particularly from hospitals and other healthcare facilities, is considered to be a reservoir for multidrug-resistant bacteria.
Cantón, Rafael, Chakraborty, Trinad, Dominguez, Lucas, Falgenhauer, Linda, Imirzalioglu, Can, Lazaro-Perona, Fernando, Mingorance, Jesús, Valverde, Aránzazu, Yao, Yancheng   +8 more
core   +1 more source

Regulatory mechanism of heat-active retrotransposons by the SET domain protein SUVH2

Frontiers in Plant Science
New transposon insertions are deleterious to genome stability. The RNA-directed DNA methylation (RdDM) pathway evolved to regulate transposon activity via DNA methylation.
Xiaoying Niu, Zhiyu Ge, Hidetaka Ito
doaj   +1 more source

Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development [PDF]

, 2014
Peer reviewedPublisher ...
Adams JC, Agathocleous M, Aihara K, Amy S. Findlay, Austin CP, Cayouette M, Cepko CL, Chizu Nakamoto, de Iongh R, Ehrlich D, Elaine Durward, Ewa D. Zakrzewska, Fekete DM, Flanagan JG, Frade JM, Galvez JM, Hansen MJ, Harada H, Harpavat S, Hashimoto T, Holt CE, Hu WY, Isenmann S, Jablonski MM, Jablonski MM, Jiang Y, Jiang Y, Katahira T, Koga A, Kuroda S, Layer PG, Marianne Bronner, Martinez-Morales JR, Masai I, Masaru Nakamoto, Matsuhashi S, Matsuhashi S, Matsuoka H, Matsuyama S, Matsuyama S, McCabe KL, McCabe KL, McLaughlin T, Moore SW, Munemasa Y, Nakamura R, Nelson BR, Nelson BR, Oyasu M, Patel A, Prada C, Price J, Rachel RA, Raymond SM, Sato Y, Snow RL, Soh-Leh Kuan, Stiemke MM, Strauss O, Takuma Endo, Wang JT, Watanabe TK, Wetts R, Xiang M, Yee JK, Zhang XM, Zhang XM, Zhufeng Ouyang   +67 more
core   +1 more source

SLFN11 Restricts LINE-1 Mobility

Cells
Long interspersed element-1 (LINE-1) is the only active autonomous transposon comprising about 17% of human genomes. LINE-1 transposition can cause the mutation and rearrangement of the host’s genomic DNA.
Zhongjie Ye, Yuqing Duan, Ao Zhang, Zixiong Zhang, Saisai Guo, Qian Liu, Dongrong Yi, Xinlu Wang, Jianyuan Zhao, Quanjie Li, Ling Ma, Jiwei Ding, Shan Cen, Xiaoyu Li   +13 more
doaj   +1 more source

Transposon display for active DNA transposons in rice

Genes & Genetic Systems, 2007
Transposon display (TD) is a powerful technique to identify the integration site of transposons in gene tagging as a functional genomic tool for elucidating gene function. Although active endogenous DNA transposons have been used extensively for gene tagging in maize, only two active endogenous DNA transposons in rice have been identified, the 0.43-kb ...
Kyoko, Takagi, Naoko, Ishikawa, Masahiko, Maekawa, Kazuo, Tsugane, Shigeru, Iida   +4 more
openaire   +3 more sources

SnapShot: Vertebrate Transposons

Cell, 2008
Transposable elements, originally discovered in maize by Barbara McClintock, are discrete DNA segments that can insert into new chromosomal locations either by a “cut and paste” or by a “copy and paste” mechanism. Transposable elements are involved in a wide variety of biological transactions including genome alteration by element insertion or deletion
Mandal, Prabhat K., Kazazian, Haig H.
openaire   +2 more sources

Reduced mutation rate and increased transformability of transposon-free Acinetobacter baylyi ADP1-ISx [PDF]

, 2017
The genomes of most bacteria contain mobile DNA elements that can contribute to undesirable genetic instability in engineered cells. In particular, transposable insertion sequence (IS) elements can rapidly inactivate genes that are important for a ...
Barrick, Jeffrey E, Dasgupta, Aurko, Renda, Brian A, Suárez, Gabriel A   +3 more
core   +2 more sources

Outbreak of Pseudomonas aeruginosa High-Risk Clone ST309 Serotype O11 Featuring bla_PER-1 and qnrVC6

Antibiotics
Pseudomonas aeruginosa is a leading cause of hospital-acquired infections worldwide. Biofilm production, antibiotic resistance, and a wide range of virulence factors contribute to their persistence in nosocomial environments.
Romina Papa-Ezdra, Matilde Outeda, Nicolás F. Cordeiro, Lucía Araújo, Pilar Gadea, Virginia Garcia-Fulgueiras, Verónica Seija, Inés Bado, Rafael Vignoli   +8 more
doaj   +1 more source

Mutations that Separate the Functions of the Proofreading Subunit of the Escherichia coli Replicase

, 2015
The dnaQ gene of Escherichia coli encodes the Ɛ subunit of DNA polymerase III, which provides the 3\u27 - 5\u27 exonuclease proofreading activity of the replicative polymerase.
Kreuzer, Kenneth N., Whatley, Zakiya
core   +1 more source

piRNA-Guided Transposon Silencing and Response to Stress in Drosophila Germline

Viruses
Transposons are integral genome constituents that can be domesticated for host functions, but they also represent a significant threat to genome stability.
Samantha Ho, William Theurkauf, Nicholas Rice   +2 more
doaj   +1 more source