Results 101 to 110 of about 52,950 (251)
The unsung hero of science: Barbara McClintock, who won the Nobel Prize in Physiology or Medicine in 1983 for her discovery of mobile genetic elements [PDF]
The Ukrainian Biochemical JournalIn 1983, American plant biologist and cytogeneticist McClintock, one of the great loners of modern science, received the first woman scientist’s unshared Nobel Prize in Physiology or Medicine. Barbara McClintock’s research, conducted in the 1930s, long
O. P. Matyshevska +2 more
doaj +1 more source
Induction and Enhancement of Bacteriocin Production (Review)
Biotechnology and Bioengineering, EarlyView.ABSTRACT Conventionally, bacteriocins are produced by microorganisms on complex substrates, released as semi‐purified preparations or crude fermentates. These bacteriocin‐containing products often exhibit unsatisfactory purity, low active‐substance content, and high production costs, limiting their commercialization and use. This review aims to analyze
Oksana Knysh, Artur Martynov
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT The glutamine synthetase expression system is widely used for therapeutic protein biomanufacturing in Chinese hamster ovary (CHO) cells. Here, we present the design of an enhanced glutamine synthetase vector for generating CHOK1SV GS‐KO stable pools that produce recombinant proteins at multigram‐per‐liter levels. We first developed a synthetic
Yusuf B. Johari +11 more
wiley +1 more source
Genome-wide mutagenesis of Zea mays L. using RescueMu transposons [PDF]
, 2004 This article discusses genome-wide mutagenesis of Zea mays L.
Morrow, Darren J. +13 more
core +1 more source
Visualizing Specific Tubulin Isotypes and Pathogenic Variants in Cellular Microtubule Arrays
Cytoskeleton, EarlyView.ABSTRACT Eukaryotic cells depend on dynamic microtubule arrays to execute a wide range of functions vital for life. These microtubule filaments are formed through the polymerization of α/β‐tubulin proteins, which can be generated from numerous tubulin genes, or isotypes.
Sareen Fiaz +2 more
wiley +1 more source
Epigenetic interactions between transposons and genes: lessons from plants
, 2008 Transposons replicate, increase in copy number and persist in nature by moving, but insertion into genes is generally mutagenic. There is thus a strong selection for transposons that can achieve a balance between their own replication and minimal damage ...
Martienssen, R., Weil, C.
core +1 more source
Exploration, EarlyView.The deficiency of PNLDC1 exacerbates the advancement of CRC. PNLDC1 interacts with TUBB4B mRNA to regulate the p53–p21–CDK2–cyclin E2 pathway, thereby influencing the G2/M phase of the cell cycle. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related mortality, highlighting the urgent need for novel therapeutic strategies.
Lexin Liu +18 more
wiley +1 more source
Die Transposons im Genom von Dictyostelium discoideum [PDF]
, 2002 Im Rahmen eines Genomsequenzierungsprojekts für Dictyostelium discoideum wurde der Genomgehalt an Transposons eingehend untersucht. Laut Analyse existieren mindestens 18 Transposonspezies mit einem Sequenzumfang von etwa 10 % des 34 Mbp großen Genoms. Es
Szafranski, Karol
core
Implications of host ULP1-like domains in DNA transposons
, 2010 Transposable elements are known to occasionally capture host genetic material. In the case of DNA transposons, such transduplications result in pseudogenic sequences that are eventually lost. An exception is the conserved transduplicated ubiquitin-like-
Sabry, Nadia Hesham
core
Sorghum T2T pangenome highlights comprehensive genomic variation
iMetaOmics, EarlyView.Three newly assembled telomere‐to‐telomere (T2T) genomes representing wild, landrace, and transformable germplasm were integrated with seven publicly available T2T genomes to construct a graph‐based pangenome. Comparative analyses revealed extensive centromere divergence, including distinct CEN137 monomer and CEN274 dimer organization, and showed that ...
Lihua Wang +10 more
wiley +1 more source