Results 31 to 40 of about 76,361 (277)

Parallel Genomics Uncover Novel Enterococcal-Bacteriophage Interactions

open access: yesmBio, 2020
Bacteriophages (phages) have been proposed as alternative therapeutics for the treatment of multidrug-resistant bacterial infections. However, there are major gaps in our understanding of the molecular events in bacterial cells that control how bacteria ...
Anushila Chatterjee   +6 more
doaj   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode   +16 more
wiley   +1 more source

Visualization and Quantification of Transposon Activity in Caenorhabditis elegans RNAi Pathway Mutants

open access: yesG3: Genes, Genomes, Genetics, 2019
RNA silencing pathways play critical roles in maintaining quiescence of transposons in germ cells to promote genome integrity. However the precise mechanism by which different types of transposons are recognized by these pathways is not fully understood.
Dylan C. Wallis   +3 more
doaj   +1 more source

Activity of Genes with Functions in Human Williams-Beuren Syndrome Is Impacted by Mobile Element Insertions in the Gray Wolf Genome. [PDF]

open access: yes, 2018
In canines, transposon dynamics have been associated with a hyper-social behavioral syndrome, although the functional mechanism has yet to be described.
Aardema, Matthew L   +5 more
core   +2 more sources

Silencing of Euchromatic Transposable Elements as a Consequence of Nuclear Lamina Dysfunction

open access: yesCells, 2020
Transposable elements (TEs) are mobile genomic sequences that are normally repressed to avoid proliferation and genome instability. Gene silencing mechanisms repress TEs by RNA degradation or heterochromatin formation.
Valeria Cavaliere   +2 more
doaj   +1 more source

Genome sequencing analysis of a novel thermophilic strain Geobacillus sp. CX412

open access: yesFrontiers in Microbiology, 2022
The thermophilic spore-forming strain Geobacillus sp. CX412 was isolated from hot spring soil in Tengchong City, Yunnan Province, China. We sequenced the complete genome of Geobacillus sp. CX412 using PacBio SMRT Sequencing.
Xin Li   +6 more
doaj   +1 more source

Enhancement of developmental defects in the boron‐deficient maize mutant tassel‐less1 by reduced auxin levels

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView., 2023
Abstract Background Plant responses to deficiencies of the micronutrient boron are diverse and go beyond the well‐characterized function of boron in cell wall crosslinking. To explain these phenotypic discrepancies, hypotheses about interactions of boron with various phytohormones have been proposed, particularly auxin.
Michaela S. Matthes   +3 more
wiley   +1 more source

Research progress in gene editing technology

open access: yesFrontiers in Bioscience-Landmark, 2021
As a tool for modifying the genome, gene editing technology has developed rapidly in recent years, especially in the past two years. With the emergence of new gene editing technologies, such as transposon editing tools, numerous advancements have been
Sheng Huang   +9 more
doaj   +1 more source

DDM1-Mediated TE Silencing in Plants

open access: yesPlants, 2023
Epigenetic modifications are indispensable for regulating gene bodies and TE silencing. DECREASE IN DNA METHYLATION 1 (DDM1) is a chromatin remodeller involved in histone modifications and DNA methylation.
Ruth Y. Akinmusola   +2 more
doaj   +1 more source

Changes in the copy number of class II transposons in Fusarium oxysporum f. sp. radicis-cucumerinum strain V03-2g and its derivatives with broadened phytopathogenicity

open access: yesУчёные записки Казанского университета: Серия Естественные науки, 2019
Phytopathogenic strains of Fusarium oxysporum can parasitize on more than 120 species of crops and ornamental plants posing a serious danger to world agriculture. The wide range of hosts can be evidence of fast changes in the genomes of F.
D.M. Afordoanyi   +2 more
doaj   +1 more source

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