Results 51 to 60 of about 49,276 (295)
Interactions of transposons with the cellular DNA repair machinery [PDF]
, 2009 Transposons are ubiquitous components of both prokaryotic and eukaryotic genomes. Transposons are mobile genetic elements whose movement inherently involves the generation of various types of DNA damage in the genome.
Ivics, Z. +5 more
core +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Heterochromatic histone modifications at transposons in Xenopus tropicalis embryos [PDF]
, 2016 Contains fulltext : 165656.pdf (Publisher’s version ) (Open Access)Transposable elements are parasitic genomic elements that can be deleterious for host gene function and genome integrity.
Elurbe, D.M. +6 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Excision of Sleeping Beauty transposons: parameters and applications to gene therapy [PDF]
, 2004 A major problem in gene therapy is the determination of the rates at which gene transfer has occurred. Our work has focused on applications of the Sleeping Beauty (SB) transposon system as a non-viral vector for gene therapy.
Hackett, PB, Discovery Genom Inc, 614 McKinley Pl NE, Minneapolis, MN 55413 USA +5 more
core
Algorithms for determining transposons in gene sequences [PDF]
, 2022 Some genes can change their relative locations in a genome. Thus for different individuals of the same species, the orders of genes might be different. Such jumping genes are called transposons.
Wang, Yue
core +1 more source
RNA silencing proteins and small RNAs in oomycete plant pathogens and biocontrol agents
Frontiers in Microbiology, 2023 IntroductionOomycetes cause several damaging diseases of plants and animals, and some species also act as biocontrol agents on insects, fungi, and other oomycetes.
Edoardo Piombo +5 more
doaj +1 more source
Advanced Science, EarlyView.Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou +10 more
wiley +1 more source
Diversity of Harbinger-like Transposons in Teleost Fish Genomes [PDF]
, 2022 International audienceSimple Summary The study of transposable elements, which are repeated DNA sequences that can insert into new locations in genomes, is of particular interest to genome evolution, as they are sources of mutations but also of new ...
Etchegaray, Ema +9 more
core +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source