Results 171 to 180 of about 60,909 (346)

Artificial intelligence‐based echocardiographic assessment for monitoring disease progression in transthyretin cardiac amyloidosis

open access: yesEuropean Journal of Heart Failure, EarlyView.
Artificial intelligence (AI)‐based estimation of stroke volume for risk prediction in amyloid transthyretin cardiomyopathy (ATTR‐CM). ATTRv, hereditary transthyretin amyloidosis; ATTRwt, wild‐type transthyretin amyloidosis; CI, confidence interval; HR, hazard ratio; IQR, interquartile range; LVOT‐VTI, left ventricular outflow tract velocity‐time ...
Lucia Venneri   +23 more
wiley   +1 more source

Left ventricular transthyretin amyloid load and apical sparing in patients with newly confirmed transthyretin amyloid cardiomyopathy

open access: yesEuropean Journal of Heart Failure, EarlyView.
In a large cohort of patients with newly diagnosed transthyretin amyloid cardiomyopathy (ATTR‐CM), echocardiographic apical sparing was associated with increased left ventricular amyloid load and atrial remodelling. Quantitative biopsy analysis revealed that Perugini scores often failed to accurately reflect myocardial amyloid burden.
Thomas Krammer   +21 more
wiley   +1 more source

Efficacy and safety of vutrisiran in transthyretin amyloid cardiomyopathy across the age spectrum: The HELIOS‐B trial

open access: yesEuropean Journal of Heart Failure, EarlyView.
Summary of the HELIOS‐B trial design. Right: Forest (top) and spline (bottom) plots demonstrating the effect of vutrisiran versus placebo on clinical outcomes across age groups in HELIOS‐B. Age‐stratified outcomes with vutrisiran in transthyretin amyloid cardiomyopathy.
Awais Sheikh   +8 more
wiley   +1 more source

Update of Natural Compounds in Transthyretin Amyloidosis, Years 2020–2025

open access: yesCrystals
Transthyretin amyloidosis (ATTR) is a disease caused by the deposition of transthyretin-derived fibrils in the body. Despite extensive research conducted over the years, there are currently only four drugs available in clinical use to treat this ...
Carlo Marotta   +2 more
doaj   +1 more source

Cardiac amyloidosis: a review and report of a new transthyretin (prealbumin) variant. [PDF]

open access: bronze, 1993
Amke Hesse   +6 more
openalex   +1 more source

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