Results 31 to 40 of about 61,872 (307)
The prevalence and distribution of the amyloidogenic transthyretin (TTR) V122I allele in Africa [PDF]
, 2016 Transthyretin (TTR) pV142I (rs76992529-A) is one of the 113 variants in the human TTR gene associated with systemic amyloidosis. It results from a G to A transition at a CG dinucleotide in the codon for amino acid 122 of the mature protein (TTR V122I ...
Alexander, Alice A +10 more
core +1 more source
Diagnostic pathways to wild‐type transthyretin amyloid cardiomyopathy: a multicentre network study
European Journal of Heart Failure, 2023 Epidemiology of wild‐type transthyretin cardiac amyloidosis (ATTRwt‐CA) remains poorly defined. A better characterization of pathways leading to ATTRwt‐CA diagnosis is of key importance, and potentially informative of disease course and prognosis.
G. Tini +50 more
semanticscholar +1 more source
Hereditary transthyretin amyloidosis
Нервно-мышечные болезни, 2020 Hereditary transthyretin amyloidosis is described in this review, including the TTR gene structure and mutation spectrum, the transthyretin protein structure and functions, the main clinical manifestations of transthyretin amyloidosis.
T. A. Adyan, A. V. Polyakov
doaj +1 more source
Cardiology Journal, 2022 BACKGROUND: Transthyretin amyloidosis (ATTR) is a rare, life-threatening systemic disorder. We present first findings on the cardiac hereditary ATTR in Poland.
Monika Gawor +11 more
doaj +1 more source
Structure and sequence analyses of Bacteroides proteins BVU_4064 and BF1687 reveal presence of two novel predominantly-beta domains, predicted to be involved in lipid and cell surface interactions. [PDF]
, 2015 BackgroundN-terminal domains of BVU_4064 and BF1687 proteins from Bacteroides vulgatus and Bacteroides fragilis respectively are members of the Pfam family PF12985 (DUF3869).
Aravind, L +5 more
core +2 more sources
ESC Heart Failure, 2023 Tafamidis improves prognosis in patients with transthyretin amyloid cardiomyopathy (ATTR‐CM). However, real‐world data on the therapeutic effect of tafamidis are lacking.
S. Takashio +13 more
semanticscholar +1 more source
Hereditary cardiac amyloidosis associated with Pro24Ser transthyretin mutation: a case report
Journal of Medical Case Reports, 2018 Background Transthyretin amyloidosis is a systemic disorder caused by extracellular deposition of insoluble amyloid fibrils in peripheral and autonomic nerves, heart, kidney, gastrointestinal tract, and other organs.
Hiroyuki Yamamoto +6 more
doaj +1 more source
The negative acute phase response of serum transthyretin following Streptococcus suis infection in the pig [PDF]
, 2005 Peer reviewedPublisher ...
Andresen, L O +5 more
core +3 more sources
Aggregated transthyretin is specifically packaged into placental nano-vesicles in preeclampsia
Scientific Reports, 2017 In preeclampsia, the serum levels of transthyretin, a carrier protein for thyroxine, are elevated. Transthyretin isolated from preeclamptic serum is also aggregated and can induce preeclampsia-like symptoms in pregnant IL10−/− mice.
Mancy Tong +7 more
doaj +1 more source
European Journal of Neurology, 2023 Hereditary transthyretin amyloidosis (ATTRv) is a life‐threatening disease caused by mutations in the gene encoding transthyretin (TTR). The recent therapeutic advances have underlined the importance of easily accessible, objective biomarkers of both ...
A. Romano +15 more
semanticscholar +1 more source