Results 71 to 80 of about 10,856 (192)
Serum Transthyretin Level as a Plausible Marker for Diagnosis of Child Acute Malnutrition
Biochemistry Research International, 2017 Malnutrition is a major underlying condition for mortality in children under five years of age in developing countries, particularly in Ethiopia. The most important forms of malnutrition in Ethiopia are protein and energy deficiencies.
Behailu Tsegaye +2 more
doaj +1 more source
The two shapes of the Tau protein
eLife, 2018 Tau proteins can convert from an inert shape to a misfolded shape that seeds the growth of fibers that contribute to the pathology of Alzheimer’s disease.
Jeffery W Kelly
doaj +1 more source
Interdisciplinary Medicine, EarlyView.This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang +8 more
wiley +1 more source
Fibroblasts endocytose and degrade transthyretin aggregates in transthyretin-related amyloidosis [PDF]
Laboratory Investigation, 2013 Transthyretin (TTR)-related amyloidosis is a fatal disorder characterized by systemic extracellular deposition of TTR amyloid fibrils. Mutations in the TTR gene cause an autosomal dominant form of the disease-familial amyloidotic polyneuropathy (FAP). Wild-type (WT) TTR can also form amyloid fibrils in elderly patients with senile systemic amyloidosis.
Misumi, Yohei +3 more
openaire +3 more sources
A Case of Systemic Amyloidosis Diagnosed After Excision of a Cutaneous Tumour of the Buttocks
JEADV Clinical Practice, EarlyView.ABSTRACT A 72‐year‐old Japanese man was referred to our hospital with two tumours on the buttocks. Two solitary, 2.5 × 1.5 cm‐sized, dark brown, well‐demarcated elevated plaques were observed, one on each side of the gluteal cleft, and dermoscopic examination showed comedo‐like openings, multiple milia‐like cysts, and a cerebriform pattern with ...
Tomomichi Shimizu +9 more
wiley +1 more source
, 2020 MD Benson,1 NR Dasgupta,1,2 R Rao2 1Department of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; 2Division of Cardiology, Indiana University School of Medicine, Indianapolis, IN 46040, USACorrespondence:
Rao R, Benson MD, Dasgupta NR
core
, 2016 Transthyretin (TTR) is a plasma hormone carrier protein associated with hereditary and senile forms of systemic amyloid disease, wherein slow tetramer disassembly is thought to be an obligatory step. Plasma transport of retinol is carried out exclusively
Stéphanie Deroo (1616770) +2 more
core +1 more source
Optimal‐Control 19F PROJECT Improves the Reliability of CPMG‐Derived Relaxation Rates
Magnetic Resonance in Chemistry, EarlyView.PROJECT with seedless optimal control pulses for 19F‐based protein‐ligand interaction screenings allows for a lower error in R2 estimates than those obtained with CPMG for J‐coupled fluorine signals and is indistinguishable from CPMG when the coupling is negligible, at the price of a modest reduction in SNR.
Marco Schiavina +2 more
wiley +1 more source
Low transthyretin concentration linked to adverse prognosis in elderly inpatients
BMC GeriatricsBackground To investigate the association between low transthyretin (prealbumin) concentration and mortality or readmission for all causes in elderly inpatients.
Ting Wang +9 more
doaj +1 more source
Systemic transthyretin amyloidosis: carpal tunnel syndrome in a Portuguese population (CarPoS) [PDF]
Exploration of CardiologyCarpal tunnel syndrome (CTS) is the most common type of entrapment neuropathy and affects approximately 1% to 5% of the general population, mostly patients older than 50 years.
Sofia Pimenta +11 more
doaj +1 more source