Results 71 to 80 of about 28,989 (238)
Plasma Transthyretin Levels in Sarcopenic and Non-Sarcopenic Elderly
Jurnal Penyakit Dalam IndonesiaIntroduction. Sarcopenia is a geriatric syndrome marked by an age-related decline in muscle mass, which is affected by protein intake. Transthyretin is a visceral protein used to evaluate nutritional status and acts as a positive regulator of muscle mass.
R. Ifan Arief Fahrurozi +7 more
doaj +1 more source
Mechanisms of Transthyretin Inhibition of IAPP Amyloid Formation
Biomolecules, 2021 Amyloid-formation by the islet amyloid polypeptide (IAPP), produced by the β-cells in the human pancreas, has been associated with the development of type II diabetes mellitus (T2DM).
Sanduni Wasana Jayaweera +7 more
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 809-818, April 2025.Abstract Aims This study aimed to evaluate the change of the main electrocardiographic (ECG) characteristics and their prognostic role across the main subtypes of cardiac amyloidosis [light‐chain amyloidosis (AL) and hereditary (ATTRv) and wild‐type transthyretin amyloidosis (ATTRwt)].
Alessia Argirò +20 more
wiley +1 more source
Frontiers in Neurology, 2023 IntroductionPain is a common symptom of hereditary transthyretin amyloidosis (ATTRv), however, its occurrence in late-onset ATTRv has not been investigated thoroughly. Our aim was to describe the pain experience and its impact on quality of life (QoL) in
Stefano Tozza +18 more
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya +9 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1176-1182, April 2025.Abstract Aims Transthyretin amyloid cardiomyopathy (ATTR‐CM) is an increasinglyrecognized cause of heart failure with preserved ejection fraction (HFpEF), which may be diagnosed non‐invasively using 99mTc 3,3‐diphosphono‐1,2‐propanodicarboxylic acid (DPD) scintigraphy‐based diagnostic criteria.
L. Healy +15 more
wiley +1 more source
Анналы клинической и экспериментальной неврологииHereditary transthyretin amyloidosis is a fatal systemic progressive disease caused by mutations in the transthyretin (TTR) gene, inherited in an autosomal dominant pattern, primarily affecting the peripheral and autonomic nervous systems and the heart ...
Elizaveta A. Guseva +2 more
doaj +1 more source
Cancer Reports, 2023 Background Patients with combined hepatocellular‐cholangiocarcinoma (cHCC‐CCA) have limited treatment options and poor prognosis. Tumor‐associated macrophages (TAMs) are the most abundant infiltrating immune cells in the tumor microenvironment and ...
Kun Ke +5 more
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1203-1216, April 2025.The 366 patients diagnosed with transthyretin amyloidosis cardiomyopathy (ATTR‐CM) were analyzed regarding their clinical characteristics in the first year after approval of tafamidis 61 mg for ATTR‐CM in Germany. Nearly two‐thirds of the patients were in an advanced disease stage and 64% met the key criteria of the “Transthyretin Amyloidosis ...
Richard J. Nies +23 more
wiley +1 more source
ESC Heart FailureAims Recognition of transthyretin amyloid cardiomyopathy is increasing due to advances in cardiac imaging and diagnostic strategies, but questions remain regarding disease frequency and characteristics.
Pablo Garcia‐Pavia +10 more
doaj +1 more source