Results 101 to 110 of about 7,937 (220)
The Journal of Physiology, Volume 604, Issue 4, Page 1646-1681, 15 February 2026.Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker +2 more
wiley +1 more source
Extracellular volume quantification by dynamic equilibrium cardiac computed tomography in cardiac amyloidosis. [PDF]
, 2015 Cardiac involvement determines outcome in patients with systemic amyloidosis. There is major unmet need for quantification of cardiac amyloid burden, which is currently only met in part through semi-quantitative bone scintigraphy or Cardiovascular ...
Bandula, S +10 more
core +1 more source
Euglycemic Ketoacidosis Induced by Dapagliflozin in a Non‐Diabetic Patient With Cardiac Amyloidosis
Clinical Case Reports, Volume 14, Issue 1, January 2026.ABSTRACT Dapagliflozin, though beneficial in heart failure, can rarely cause euglycemic ketoacidosis even in non‐diabetic patients. Clinicians should maintain a high index of suspicion for metabolic acidosis in patients on SGLT2 inhibitors presenting with unexplained illness, regardless of blood glucose level.
Salhamoud Abdelfatah Saleh Hamoud +1 more
wiley +1 more source
A case report in cardiovascular magnetic resonance: the contrast agent matters in amyloid [PDF]
, 2017 BACKGROUND: Cardiac amyloidosis is a progressive but underdiagnosed and underappreciated cause of heart failure. In the last few years, cardiovascular magnetic resonance (CMR) has become the gold standard for non invasive diagnosis of cardiac ...
Fontana, M +7 more
core +2 more sources
A possible role for miRNA silencing in disease phenotype variation in Swedish transthyretin V30M carriers [PDF]
, 2010 Our results are the first to show the presence of a 3'UTR polymorphism on the V30M haplotype in Swedish carriers, which can serve as a miRNA binding site potentially leading to down-regulated expression from the mutated TTR allele.
Malin Olsson +6 more
core +2 more sources
Myocardial Extracellular Volume Quantification by Cardiovascular Magnetic Resonance and Computed Tomography [PDF]
, 2018 PURPOSE OF REVIEW: This review article discusses the evolution of extracellular volume (ECV) quantification using both cardiovascular magnetic resonance (CMR) and computed tomography (CT).
Bastarrika, G +3 more
core +1 more source
Treatment With Tafamidis Slows Disease Progression in Early-Stage Transthyretin Cardiomyopathy
Clinical Medicine Insights: Cardiology, 2017 Background: Transthyretin cardiomyopathy (TTR-CM) is a progressive, fatal disease caused by the accumulation of misfolded transthyretin (TTR) amyloid fibrils in the heart.
Marla B Sultan +3 more
doaj +1 more source
Scientific ReportsThe pathophysiology of variant transthyretin (TTR) amyloidosis (ATTRv) is associated with destabilizing mutations in the TTR tetramer. However, why TTR with a wild-type genetic sequence misfolds and aggregates in wild-type transthyretin amyloidosis ...
Takuya Iino +11 more
doaj +1 more source
Journal of Medical Case Reports, 2008 Introduction Hereditary amyloidodis is a rare disease process with a propensity to cause polyneuropathies, autonomic dysfunction, and restrictive cardiomyopathy. It is transmitted in an autosomal dominant manner, with disease onset usually in the 20s-40s.
Robin Jason +7 more
doaj +1 more source
Protein-Remodeling Factors As Potential Therapeutics for Neurodegenerative Disease [PDF]
, 2017 Protein misfolding is implicated in numerous neurodegenerative disorders including amyotrophic lateral sclerosis, Parkinson's disease, Alzheimer's disease, and Huntington's disease.
James Shorter, Meredith E. Jackrel
core +1 more source