Results 131 to 140 of about 74,349 (302)

Design Thinking in Engineering Education: Fab Lab as a Transversal Space

This study investigates the interactions between Design and Engineering, two areas that, in addition to going beyond their traditional boundaries, dialogue with other disciplines in search of innovative solutions to contemporary challenges.
Alquezar Facca, Claudia, Mortensen Steagall, Marcos (Translator)   +1 more
core   +1 more source

PoolHiTS: A Shifted Transversal Design based pooling strategy for high-throughput drug screening-2

, 2011
(= 100) and various choices of expected active compounds (). The trend suggests that the ability to correct for experimental assay error-rates decreases as increases.Copyright information:Taken from "poolHiTS: A Shifted Transversal Design based pooling ...
Raghunandan M Kainkaryam (87719), Peter J Woolf (87720)   +1 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Percurso cartográfico na Comunidade Quilombola Grilo: uma análise da atuação transversal do design

The present work is an investigation into the role of a designer and researcher in a traditional community, analyzing the possibility of a transversal role of a white designer in a quilombola community. The work is characterized as intervention research,
Teles da Silva, Julia, Campos Silva, Alice, Barros da Mota Silveira, Nathalie   +2 more
core   +1 more source

Business by design : comunicare il valore strategico del design. Metodi e modelli di integrazione del design nell'ambito business

, 2020
LAUREA MAGISTRALEQuesta tesi di laurea nasce a partire dalle recenti esperienze lavorative del candidato, maturate in ambienti non propriamente “consueti”, se così potremmo dire, al più classico ruolo di un designer della comunicazione; la prima nel ...
BROTTO, FRANCESCA
core  

Private Information Retrieval Protocols Based on Transversal Designs

, 2021
Målet med denne thesis er at undersøge et transversal design baseret private information retrival scheme. Konstruktionen af $1$-private og $(t-1)$-private PIR protokoller vil blive forklaret og deres egenskaber vist. Konstruktionen af transversal designs
Martinsen, Christian Juel
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Improving design coordination in computer supported environments in SMEs : implementation of a tool for capturing and analysing collaboration between actors [PDF]

, 2007
To remain competitive in a context of multi-partner projects companies are increasingly concerned with the coordination of design projects. Information systems such as PLM or CSCW are implemented to support the coordination of product information flows.
Pol, Guillaume
core  

Acquisition of transversal competencies through a project-based learning model for computer systems engineering students

Frontiers in Education
IntroductionThis article presents an innovative educational practice to promote transversal competences in computer engineering university students, through Project Based Learning (PjBL), providing students with the benefit of experiential learning ...
Julieta Noguez, Enedina Ortega Gutiérrez, Luis Neri, Julio E. Rubio   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source