Results 141 to 150 of about 74,349 (302)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The pre-things and transversal activity of Manoel de Barros: a contribution to the creative process in design [PDF]

, 2014
Carina P. Carlan, Carlan, Carina Prina, José L. F. Aymone, Aymone, Jose Luis Farinatti   +3 more
core   +1 more source

Perspectives of medicine, human biology, and nursing undergraduates on transversal skills learning: a mixed-methods study

BMC Medical Education
Background In health sciences practice, interpersonal skills, critical thinking, and learning-to-learn are crucial transversal skills. Effective teaching necessitates the understanding of undergraduates’ views.
Nathalia Silva Fontana-Rosa, Luis González-de Paz, Ana C. Codina-Rodríguez, María Pérez-Riart, María del Mar Carrió-Llach   +4 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Evaluación de los indicadores epidemiológicos del programa de la tuberculosis: Matanzas. Años 2002- 2006 Evaluating the epidemiological indicators of the tuberculosis program: Matanzas.Years 2002-2006

Revista Médica Electrónica, 2009
Se realizó una Investigación en Sistemas y Servicios de Salud (ISSS) con un diseño epidemiológico observacional de tipo descriptivo transversal en la provincia de Matanzas en el período 2000-2006.Se tomaron el 100% de los casos de tuberculosis ...
Pedro R Gómez Murcia, Fernando Achiong Estupiñán, José M Morales Rigau, Leovaldo Núñez Valdés, Jesús Quintana Hernández, Carmen Gloria Pérez Fundora   +5 more
doaj  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Transversal Architecture for Megaquop-Scale Quantum Simulation with Neutral Atoms

PRX Quantum
Quantum computing experiments have made remarkable progress in demonstrating key components of error-corrected quantum computing, a prerequisite for scalable quantum computation.
Refaat Ismail, I-Chi Chen, Chen Zhao, Ronen Weiss, Fangli Liu, Hengyun Zhou, Sheng-Tao Wang, Andrew Sornborger, Milan Kornjača   +8 more
doaj   +1 more source