Results 81 to 90 of about 615,852 (293)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

AoMbp1 Governs Conidiation and Trap Morphogenesis in Arthrobotrys oligospora Via Direct Transcriptional Activation of the MAPK Sensor AoSho1

Journal of Fungi
The nematode-trapping fungus (NTF) Arthrobotrys oligospora (A. oligospora) is a promising biocontrol agent, but the transcriptional regulators governing its predation remain poorly understood.
Ruobing Li, Lixiang Wei, Yanseng Sun, Chengzhi Zhang, Yuhang Nie, Qinglong Meng, Shuang Chen, Ming Wu, Xuepeng Cai, Jie Li, Qingling Meng, Jun Qiao   +11 more
doaj   +1 more source

Formation of a vortex lattice in a rotating BCS Fermi gas [PDF]

, 2006
We investigate theoretically the formation of a vortex lattice in a superfluid two-spin component Fermi gas in a rotating harmonic trap, in a BCS-type regime of condensed non-bosonic pairs. Our analytical solution of the superfluid hydrodynamic equations,
Amoruso, Astrakharchik, Bartenstein, Bourdel, Carlson, Castin, Chin, Cozzini, Dalfovo, F. Werner, Feder, Feder, G. Tonini, Greiner, Hodby, Isoshima, Leggett, Lobo, Madison, Madison, Menotti, Mora, Nygaard, O'Hara, paper, Petrov, Randeria, Recati, Regal, Sinha, Stringari, Törmä, Wigner, Y. Castin   +33 more
core   +3 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Genomic and Transcriptomic Analyses Revealed DdSTE2 Play a Role in Constricting Ring Formation in the Nematode-Trapping Fungi Drechslerella dactyloides

Microorganisms
The carnivorous fungus Drechslerella dactyloides can form constricting rings through hyphal specialization to capture nematodes. The formation of constricting rings is a prerequisite for capturing nematodes and a characteristic of entering the ...
Cheng-Lin Wu, Ren-Qiao Wang, Jin-Ting Yang, Jia-Mei Sun, Yan-Rui Xu, Jianping Xu, Ke-Qin Zhang, Lian-Ming Liang   +7 more
doaj   +1 more source

Quantum dynamics of resonant molecule formation in waveguides

, 2009
We explore the quantum dynamics of heteronuclear atomic collisions in waveguides and demonstrate the existence of a novel mechanism for the resonant formation of polar molecules.
Melezhik, Vladimir S., Schmelcher, Peter
core   +1 more source

Dynamical Instability of a Rotating Dipolar Bose-Einstein Condensate [PDF]

, 2007
We calculate the hydrodynamic solutions for a dilute Bose-Einstein condensate with long-range dipolar interactions in a rotating, elliptical harmonic trap, and analyse their dynamical stability.
A. M. Martin, D. H. J. O’Dell, L. Pitaevskii, N. G. Parker, R. M. W. van Bijnen, Y. Castin   +5 more
core   +3 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Transfer and scattering of wave packets by a nonlinear trap

, 2011
In the framework of a one-dimensional model with a tightly localized self-attractive nonlinearity, we study the formation and transfer (dragging) of a trapped mode by "nonlinear tweezers", as well as the scattering of coherent linear wave packets on the ...
A. Degasperis, Boris A. Malomed, D. J. Frantzeskakis, J. J. Sakurai, Kai Li, M. Abramowitz, P. G. Kevrekidis, R. Carretero-González, T. Dauxois, W. A. Harrison   +9 more
core   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source