Results 111 to 120 of about 5,909 (202)
ABSTRACT Background and Aims Despite lacking evidence, homeopathy continues to enjoy high levels of usage and general acceptance. Particularly concerning the treatment of cancer, this can pose risks, especially when it leads to delay or replacement of evidence‐based treatments.
Maximilian Gimbel +8 more
wiley +1 more source
ABSTRACT Background and Aims Transfusion‐dependent beta‐thalassemia is a chronic hematologic disorder necessitating lifelong blood transfusions and iron chelation therapy, which can lead to systemic and ocular complications. This study aimed to assess the frequency and characteristics of ocular complications in beta‐thalassemia patients treated with ...
Abdolreza Medghalchi +7 more
wiley +1 more source
SIRT Family: Biological Functions and Therapeutic Targets
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang +9 more
wiley +1 more source
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy +8 more
wiley +1 more source
Under oxidative and excitotoxic stress, Müller cell‐derived 5′tiRNA‐His‐GTG contributes to retinal neurodegeneration. Pathological stimuli increase ANG‐dependent production of 5′tiRNA‐His‐GTG, which suppresses LPCAT1 expression and disrupts phosphatidylcholine (PC)‐mediated glycerophospholipid metabolism.
Yuke Ji +9 more
wiley +1 more source
The study found that SARS‐CoV‐2 Omicron infection causes region‐specific inflammatory, immune, synaptic, and signaling disorders in the brain, and the predicted kinases and differentially expressed proteins may serve as potential targets for COVID‐19‐related drug discovery.
Qiaochu Wang +8 more
wiley +1 more source
Interocular Comparison of Refractive Development in Children With Unilateral Traumatic Optic Neuropathy. [PDF]
Liao L +6 more
europepmc +1 more source
Abstract Background Medial branch blocks (MBB) and radiofrequency ablations (RFA) are common diagnostic, prognostic, and interventional procedures performed for the management of cervical and lumbar spine facetogenic pain. Although these procedures have established utility as pain management strategies, it is unclear if the disruption in function of ...
Matthew Carter +6 more
wiley +1 more source
MOG Antibody-Associated Optic Neuritis Masquerading as Traumatic Optic Neuropathy Following Cranial Trauma: A Case Report. [PDF]
Shi Y +5 more
europepmc +1 more source
Clinical profile and visual outcome in patients with traumatic optic neuropathy. [PDF]
Sujithra H, Shah K, Greeshma C.
europepmc +1 more source

